[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100521519":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":42,"centralContacts":46,"locations":55,"responsibleParty":74,"collaborators":77,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":85,"acronym":41,"eligibilityCriteria":86,"healthyVolunteers":83,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":41,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":41,"overallStatus":58,"whyStopped":41,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Yale University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1","ACTIVE_COMPARATOR","Bolus of 0.3mg\u002Fkg\u002Fmin DMT (5min) + Normal Saline infusion (60 min)",[13],"Drug: 0.3mg\u002Fkg\u002Fmin Dimethyltryptamine + Normal Saline infusion",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2","Bolus of 0.2 mg\u002Fkg\u002Fmin DMT (5 min) + 0.01mg\u002Fkg\u002Fmin infusion (60 min)",[18],"Drug: 0.2 mg\u002Fkg\u002Fmin + Dimethyltryptamine 0.01mg\u002Fkg\u002Fmin infusion",{"label":20,"type":21,"description":22,"interventionNames":23},"Group 3","PLACEBO_COMPARATOR","Bolus of 25 mg Diphenhydramine (5 min) + Normal Saline infusion (60 min)",[24],"Drug: 25 mg Diphenhydramine (5 min) + Normal Saline",[26,33,38],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","0.3mg\u002Fkg\u002Fmin Dimethyltryptamine + Normal Saline infusion","Infusion",[9],[32],"Moderate Dose DMT",{"type":27,"name":34,"description":29,"armGroupLabels":35,"otherNames":36},"0.2 mg\u002Fkg\u002Fmin + Dimethyltryptamine 0.01mg\u002Fkg\u002Fmin infusion",[15],[37],"Low Dose DMT",{"type":27,"name":39,"description":29,"armGroupLabels":40,"otherNames":41},"25 mg Diphenhydramine (5 min) + Normal Saline",[20],null,[43],{"name":44,"affiliation":5,"role":45},"Anahita Bassir Nia, MD","PRINCIPAL_INVESTIGATOR",[47,52],{"name":48,"role":49,"phone":50,"phoneExt":41,"email":51},"Angelina Contreras","CONTACT","(203) 974-7525","angelina.contreras@yale.edu",{"name":53,"role":49,"phone":41,"phoneExt":41,"email":54},"Ardavan Mohammad Aghaei","ardavan.mohammadaghaei@yale.edu",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Connecticut Mental Health Center","RECRUITING","New Haven","Connecticut","06519","United States","US",{"type":65,"coordinates":66},"Point",[67,68],-72.92816,41.30815,{"lat":68,"lon":67},[71,73],{"name":44,"role":49,"phone":41,"phoneExt":41,"email":72},"anahita.bassirnia@yale.edu",{"name":44,"role":45,"phone":41,"phoneExt":41,"email":41},{"type":45,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":41,"oldOrganization":41},"Anahita Bassir Nia","Assistant Professor of Psychiatry",[78],{"name":79,"class":80},"National Institute on Alcohol Abuse and Alcoholism (NIAAA)","NIH","100521519","phase-1-the-potential-therapeutic-effects-of-psychedelic-n-n-dimethyltryptamine-dmt-on-alcohol-use-disorder-aud-100521519",false,"NCT06070649","The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)","Inclusion Criteria:\n\n* Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5) diagnosis of Alcohol Use Disorder\n* Medically healthy\n* Ability to provide consent\n\nExclusion Criteria:\n\n* Unstable medical conditions","ALL","21 Years","65 Years",{"count":91,"type":92},63,"ESTIMATED","INTERVENTIONAL",[95],"PHASE1","This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.",[98,99,100],"Alcohol Use Disorder (AUD)","Alcohol-Related Disorders","Alcohol Use","2026-04-26",{"date":103,"type":104},"2026-04-28","ACTUAL",{"date":106,"type":104},"2025-08-04",{"date":108,"type":92},"2026-08-01",{"name":5,"class":6},1]