[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620881":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":61,"collaborators":24,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":24,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":24,"studyType":76,"phases":77,"briefSummary":80,"conditions":81,"keywords":24,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"First Affiliated Hospital of Fujian Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"68Ga-G21 PET imaging","EXPERIMENTAL","Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-G21. Tracer of 68Ga-G21 will be used to image lesions of prostate cancer by PET imaging.",[13],"Drug: 68Ga-G21",{"label":15,"type":10,"description":16,"interventionNames":17},"68Ga-G23 PET imaging","Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-G23. Tracer of 68Ga-G23 will be used to image lesions of prostate cancer by PET imaging.",[18],"Drug: 68Ga-G23",[20,25],{"type":21,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"DRUG","68Ga-G21",[9],null,{"type":21,"name":26,"description":16,"armGroupLabels":27,"otherNames":24},"68Ga-G23",[15],[29],{"name":30,"affiliation":5,"role":31},"Weibing Miao, MD","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","86-0591-87981618","miaoweibing@126.com",{"name":38,"role":34,"phone":39,"phoneExt":24,"email":40},"Guochang Wang, MD","86-0591-87981619","guochang1007@163.com",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University","RECRUITING","Fuzhou","Fujian","350005","China","CN",{"type":51,"coordinates":52},"Point",[53,54],119.30611,26.06139,{"lat":54,"lon":53},[57,59],{"name":30,"role":34,"phone":58,"phoneExt":24,"email":36},"+86-0591 87981618",{"name":38,"role":34,"phone":60,"phoneExt":24,"email":40},"+86-0591-87981619",{"type":62,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100620881","phase-1-the-value-of-grpr-pet-imaging-for-diagnosis-and-staging-in-prostate-cancer-100620881",false,"NCT07363382","The Value of GRPR PET Imaging for Diagnosis and Staging in Prostate Cancer","The Value of Gastrin-Releasing Peptide Receptor (GRPR) PET Imaging for Diagnosis and Staging in Prostate Cancer","Inclusion Criteria:\n\n* confirmed treated or untreated prostate cancer patients;\n* signed written consent.\n\nExclusion Criteria:\n\n* known allergy against PSMA;\n* any medical condition that in the opinion of the investigator may significantly interfere with study compliance.","MALE","18 Years","90 Years",{"count":74,"type":75},6,"ESTIMATED","INTERVENTIONAL",[78,79],"PHASE1","PHASE2","The gastrin-releasing peptide receptor (GRPR) is highly expressed in prostate cancer (77%-100%). Numerous studies have confirmed that GRPR PET imaging has emerged as a significant molecular imaging modality in prostate cancer, particularly serving as a complementary tool to PSMA PET for addressing cases with negative or insufficient PSMA expression. It demonstrates substantial value in initial staging (especially in intermediate- and high-risk patients), detecting sites of biochemical recurrence, assessing metastatic lesions (notably in mCRPC), and guiding treatment decisions. 68Ga-G21 and 68Ga-G23 are two novel molecular probes targeting GRPR. This study aims to evaluate their biodistribution and diagnostic performance in prostate cancer and compare them with 68Ga-PSMA-11 PET imaging.",[82],"Prostate Cancer (Adenocarcinoma)","2026-01-16",{"date":85,"type":86},"2026-01-23","ACTUAL",{"date":88,"type":86},"2025-12-20",{"date":90,"type":75},"2027-12-31",{"name":5,"class":6},1]