[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552504":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":29,"centralContacts":40,"locations":29,"responsibleParty":47,"collaborators":29,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":29,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":29,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":29,"overallStatus":69,"whyStopped":29,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":29},{"fullName":5,"class":6},"Jemincare","INDUSTRY",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort 1","EXPERIMENTAL","Participants will receive JMKX001899 500 once on Day 1",[13,14],"Drug: JMKX001899","Drug: Placebo",{"label":16,"type":10,"description":17,"interventionNames":18},"Cohort 2","Participants will receive JMKX001899 750 once on Day 1",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Cohort 3","Participants will receive JMKX001899 1000 once on Day 1",[13,14],[24,30,33,36],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DRUG","JMKX001899","Participants will receive JMKX001899 500mg tablet, orally once on Day 1",[9],null,{"type":25,"name":26,"description":31,"armGroupLabels":32,"otherNames":29},"Participants will receive JMKX001899 750mg tablet, orally once on Day 1",[16],{"type":25,"name":26,"description":34,"armGroupLabels":35,"otherNames":29},"Participants will receive JMKX001899 1000mg tablet, orally once on Day 1",[20],{"type":25,"name":37,"description":38,"armGroupLabels":39,"otherNames":29},"Placebo","Participants will receive JMKX001899 matching placebo, tablet, orally once on Day 1",[9,16,20],[41],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},"WEIXIA LI","CONTACT","15000279084","+86","liweixia@jemincare.com",{"type":48,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100552504","phase-1-to-assess-the-effects-of-single-dose-of-jmkx001899-on-qtc-interval-in-healthy-subjects-100552504",false,"NCT06473948","To Assess the Effects of Single Dose of JMKX001899 on QTc Interval in Healthy Subjects","A Phase 1, Single Center, Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Effect of JMKX001899 on the QTc Interval in Healthy Subjects","Inclusion Criteria:\n\n1. Healthy, adult, male or female 18-45 years of age, inclusive.\n2. Body mass index (BMI) between 19 and 28 kg\u002Fm2 (inclusive) and weight at least 50 kg.\n3. Participant must sign an informed consent form (ICF) indicating that he or she understands the purpose of, and procedures required for, the study and is willing to participate in the study.\n\nExclusion Criteria:\n\n1. Patients with a history of clinically significant diseases including, but not limited to, gastrointestinal, renal, liver, neurological, hematological, endocrine, neoplastic, pulmonary, immune, psychiatric, or cardiovascular and cerebrovascular diseases, epilepsy, bipolar disorder\u002Fmania, intraocular hypertension, or acute angle-closure glaucoma.\n2. Female subjects with a positive pregnancy test or lactating.\n3. Positive results at screening for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAg), hepatitis C virus (HCV) or Treponema pallidum（TP-Ab）",true,"ALL","18 Years","45 Years",{"count":61,"type":62},27,"ESTIMATED","INTERVENTIONAL",[65],"PHASE1","Study to assess the effect of JMKX001899 on QTc interval in healthy volunteers",[68],"Solid Tumor, Adult","NOT_YET_RECRUITING","2024-06-19",{"date":72,"type":73},"2024-06-25","ACTUAL",{"date":75,"type":62},"2024-07-10",{"date":77,"type":62},"2025-02-27",{"name":5,"class":6}]