[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100230011":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":36,"responsibleParty":53,"collaborators":30,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":30,"enrollmentInfo":66,"targetDuration":30,"studyType":69,"phases":70,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":39,"whyStopped":30,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Children's Hospital Medical Center, Cincinnati","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hyperpolarized 129 Xenon","EXPERIMENTAL","Administration of up to 1 liter doses of Hyperpolarized Xenon gas during MRI (less for children) to optimize acquisition of images for children and adults vs. proton MR imaging",[13],"Drug: Hyperpolarized 129 Xenon",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DRUG","During the scans, subject will inhale hyperpolarized Xenon gas for up to 16 seconds per scan, for up to 4 separate MR scans",[9],[20],"HP 129 Xe",[22],{"name":23,"affiliation":5,"role":24},"Jason C. Woods, PhD","PRINCIPAL_INVESTIGATOR",[26,32],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Carrie Stevens, BS","CONTACT","513-636-9973",null,"Carrie.Stevens@cchmc.org",{"name":33,"role":28,"phone":34,"phoneExt":30,"email":35},"Kelly Thornton, BS","513-636-0604","Kelly.Thornton@cchmc.org",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Cincinnati Children's Hospital Medical Center","RECRUITING","Cincinnati","Ohio","45229","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-84.51439,39.12711,{"lat":49,"lon":48},[52],{"name":23,"role":24,"phone":30,"phoneExt":30,"email":30},{"type":54,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100230011","phase-1-use-of-hyperpolarized-xenon-gas-for-lung-imaging-in-children-and-adults-100230011",false,"NCT02272049","Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults","Use of Hyperpolarized 129 Xe MR Lung Imaging in Children and Adults","HPXeMR","Inclusion Criteria:\n\n* Ages 6 and up\n* Participant must be able to hold breath for up to 16 seconds\n\nExclusion Criteria:\n\n* History of heart defect\n* Pregnancy or positive pregnancy test\n* History of uncontrolled asthma defined for this study as requiring use of rescue inhaler ≥ 2 times in past month\n* Symptoms of respiratory infection (loose or productive cough or wheeze), chest tightness, or sinus infection within past week\n* Baseline oximetry at MRI visit of less than 95% on room air or less than 95% on a previously prescribed dosage of oxygen delivered by nasal cannula\n* Participant is claustrophobic and unable to tolerate the imaging.\n* Standard MRI exclusions (metal, implants)",true,"ALL","6 Years",{"count":67,"type":68},300,"ESTIMATED","INTERVENTIONAL",[71,72],"PHASE1","PHASE2","The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of children and adults and in adults and also in children with respiratory compromise due to a variety of diseases.",[75],"Respiratory Disorders",[77],"Respiratory","2026-02-12",{"date":80,"type":81},"2026-02-17","ACTUAL",{"date":83,"type":81},"2014-12",{"date":85,"type":68},"2029-08-31",{"name":5,"class":6},1]