[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587925":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":24,"collaborators":11,"id":28,"slug":29,"hasResults":30,"nctId":31,"briefTitle":32,"officialTitle":33,"acronym":11,"eligibilityCriteria":34,"healthyVolunteers":35,"sex":36,"minAge":37,"maxAge":38,"enrollmentInfo":39,"targetDuration":11,"studyType":42,"phases":43,"briefSummary":46,"conditions":47,"keywords":11,"overallStatus":55,"whyStopped":11,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":11},{"fullName":5,"class":6},"Hong Kong University of Science and Technology","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental","EXPERIMENTAL",null,[13],"Behavioral: aPAVRCT",{"label":15,"type":16,"description":17,"interventionNames":11},"control","NO_INTERVENTION","usual care (PA)",[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"BEHAVIORAL","aPAVRCT","* We offered a system integrated with an indoor bike (for physical activity) and a multisensory VR environment (for cognitive training, such as reminiscence).\n* Participants will actively navigate the virtual environment by pedaling and steering the handlebar.\n* Care professionals will deliver the intervention using this system.",[9],{"type":25,"investigatorFullName":26,"investigatorTitle":27,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","GE LIN KAN","Professor","100587925","phase-1-vr-based-physical-activity-and-reminiscence-therapy-100587925",false,"NCT06934720","VR-based Physical Activity and Reminiscence Therapy","Active Physical Activity - Virtual Reality Cognitive Therapy","Inclusion Criteria:\n\n* older adults in the setting who have the ability to pedal the rehabilitation bike\n\nExclusion Criteria:\n\n* Individuals self-reporting or identified by stakeholders as unwilling or unsuitable to participate.",true,"ALL","60 Years","100 Years",{"count":40,"type":41},100,"ESTIMATED","INTERVENTIONAL",[44,45],"PHASE1","PHASE2","The goal of this clinical trial is to learn if active Physical activity + virtual reality cognitive therapy (aPAVRCT) works to slow the progression of AD cognitive decline in older adults. It will also learn about the physical effects and mental effects of the aPAVRCT. The main questions it aims to answer are:\n\nDoes aPAVRCT slow the progression of AD cognitive decline? (e.g., HK-MoCA, ADAS-Cog) Does aPAVRCT improve physical function? (e.g., ADL) Does aPAVRCT improve mental health? (e.g., GDS-15, PANAS) Does aPAVRCT improve life satisfaction? Does aPAVRCT improve other cognitive or physical capacities? What issues and benefits do participants and stakeholders (e.g., families, caregivers, managers) have when taking aPAVRCT? (e.g., NPI-Q) Researchers will compare the intervention group (aPAVRCT) to a control group (rehabilitation bike) to see if aPAVRCT works to slow the progression of AD in cognitive decline.\n\nParticipants will:\n\nTake aPAVRCT (interventional group) or usual physical acitvity (control group) at least twice a week, 15 minutes for each session, for 12-16 weeks Physiotherapies (assistants) and care professionals will do the intervention, research group will operate, observe, and assist the experiment.\n\nAll the experiment processes will be recorded. Visit the sites everyday for checkups and tests Keep a diary of their symptoms, the number of times, and any essential information\n\nSites: around 3-5 nursing homes, under one institution. Inclusion criteria: older adults in the setting who have the ability to pedal a rehabilitation bike.",[48,49,50,51,52,53,54],"Dementia","Neurodegenerative Disease","Mild Cognitive Impairment (MCI)","Virtual Reality","Physical Activity","Alzheimer's Disease (AD)","Cognitive Therapy","NOT_YET_RECRUITING","2025-05-18",{"date":58,"type":59},"2025-05-22","ACTUAL",{"date":61,"type":41},"2025-05-19",{"date":63,"type":41},"2027-04-15",{"name":5,"class":6}]