[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545382":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":47,"centralContacts":48,"locations":58,"responsibleParty":74,"collaborators":47,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":47,"studyType":92,"phases":93,"briefSummary":96,"conditions":97,"keywords":47,"overallStatus":103,"whyStopped":47,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Wayne State University","OTHER",[8,14,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"THC Group","EXPERIMENTAL","Cannabis with 5 mg THC; up to a maximum of 5 doses\u002Fday (max dose = 25 mg THC)",[13],"Drug: Tetrahydrocannabinol",{"label":15,"type":10,"description":16,"interventionNames":17},"CBD Group","Cannabis with 5 mg CBD; up to a maximum of 5 doses\u002Fday (max dose = 25 mg CBD)",[18],"Drug: Cannabidiol",{"label":20,"type":10,"description":21,"interventionNames":22},"THC & CBD Group","Cannabis with 5 mg THC and 5 mg CBD; up to a maximum of 5 doses\u002Fday (max doses = 25 mg THC and 25 mg CBD)",[13,18],{"label":24,"type":25,"description":26,"interventionNames":27},"Placebo Group","ACTIVE_COMPARATOR","Cannabis with \\\u003C1mg THC and \\\u003C1mg CBD; up to a maximum of 5 doses\u002Fday (max dose = \\\u003C5 mg THC and \\\u003C5 mg CBD)",[28],"Drug: Placebo",[30,37,43],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DRUG","Tetrahydrocannabinol","Plant cannabis that will be smoked",[20,9],[36],"THC",{"type":31,"name":38,"description":39,"armGroupLabels":40,"otherNames":41},"Cannabidiol","Plant cannabidiol that will be smoked",[15,20],[42],"CBD",{"type":31,"name":44,"description":45,"armGroupLabels":46,"otherNames":47},"Placebo","Plant will be smoked.",[24],null,[49,54],{"name":50,"role":51,"phone":52,"phoneExt":47,"email":53},"Leslie Lundahl, PhD","CONTACT","3139931374","llundahl@wayne.med.edu",{"name":55,"role":51,"phone":56,"phoneExt":47,"email":57},"Paula Qefaliaj, B.S.","2487168321","paulaq@wayne.edu",[59],{"facility":5,"status":47,"city":60,"state":61,"zip":62,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":71},"Detroit","Michigan","48201","United States","US",{"type":66,"coordinates":67},"Point",[68,69],-83.04575,42.33143,{"lat":69,"lon":68},[72],{"name":73,"role":51,"phone":47,"phoneExt":47,"email":47},"Nareen Sadik, B.S.",{"type":75,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"PRINCIPAL_INVESTIGATOR","Leslie Lundahl","Professor","100545382","phase-1-warrior-care-cannabis-behavioral-health-100545382",false,"NCT06381180","Warrior CARE: Cannabis Behavioral Health","Wayne Warrior CAnnabis Research and Education: Cannabis and Behavioral Health","CBH","Inclusion Criteria:\n\n* a healthy veteran who has served in a branch of the US armed forces\n* report using cannabis within the past year\n* currently meet DSM-5 criteria for PTSD and a score of 25 or greater on the CAPS-5 (the anchor, or index, trauma does not have to be related to military service)\n* between the ages of 19-69 years old\n* not seeking treatment for Cannabis Use Disorder\n* stable (i.e., under the care of a physician or therapist and not experiencing acute symptoms) on psychotropic medications and\u002For psychotherapy before the study begins (participants can be in treatment for PTSD)\n* agree to adhere to study procedures\n\nExclusion Criteria:\n\n* pregnant, lactating, or heterosexually active women and not using medically approved birth control\n* current or past bipolar or psychotic disorder as determined using the SCID-5\n* at immediate high risk for suicide based on the C-SSRS\n* current SUD other than Nicotine Use Disorder and Alcohol Use Disorder (mild or moderate)\n* allergies and\u002For other contradictions for using cannabis\n* any clinically significant medical problems\n* systolic\u002Fdiastolic BP \\>140\u002F90 mmHg or systolic BP \\\u003C95 mmHg\n* elevated liver function tests\n* exhibit cognitive impairment (\\\u003C80 IQ)\n* enrolled in another clinical trial or have received any drug as part of a research study within 30 days of dosing\n* used a prescription medication (with the exception of birth control) within 14 days of study entry that in the opinion of the medically responsible investigator will interfere with the safety of the participant or the study results\n* unable to provide informed consent","ALL","19 Years","69 Years",{"count":90,"type":91},500,"ESTIMATED","INTERVENTIONAL",[94,95],"PHASE1","PHASE2","This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideation.",[98,99,100,101,102],"Post Traumatic Stress Disorder","Cannabis Use","Suicide","Veterans","Marijuana","NOT_YET_RECRUITING","2025-09-23",{"date":106,"type":107},"2025-09-29","ACTUAL",{"date":109,"type":91},"2025-09-22",{"date":111,"type":91},"2030-12-31",{"name":5,"class":6},1]