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months\n* Ongoing major and active psychiatric disorder and\u002For other concurrent medical condition that, in the opinion of the Investigator, might compromise safety and\u002For compliance with study requirements.\n* History of alcohol or drug abuse within the previous 2 years.\n* Poorly controlled clinically significant medical illness, such as hypertension (blood pressure \\>180 mmHg systolic or 100 mmHg diastolic); myocardial infarction within 6 months; uncompensated congestive heart failure or other significant cardiovascular, pulmonary, renal, liver, infectious disease, immune disorder, or metabolic\u002Fendocrine disorders or other disease that would interfere with assessment of drug safety in the opinion of the Investigator.\n* Abnormal laboratory tests that, in the Investigator's assessment, mean that a participant is not appropriate for participation in this study, including, but not limited to:\n\n  1. Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) \\>2.0\n\n     × the upper limit of normal (ULN),\n  2. Total bilirubin \\>1.5 × ULN, and\u002For\n  3. International Normalised Ratio (INR) \\>1.5 NOTE: Participants with Gilbert's syndrome can be included with total bilirubin \\>1.5 x ULN as long as direct bilirubin is ≤ 1.5 x ULN)","ALL","45 Years",{"count":226,"type":227},90,"ESTIMATED","INTERVENTIONAL",[230],"PHASE2","The purpose of this interventional study is to determine whether neflamapimod can improve residual physical disability and\u002For cognitive dysfunction after Moderate to Severe Acute Ischaemic Stroke.",[233,234],"Moderate to Severe Acute Ischaemic Stroke","Ischaemic Stroke","2026-02-05",{"date":237,"type":238},"2026-02-09","ACTUAL",{"date":240,"type":238},"2025-06-20",{"date":242,"type":227},"2026-06-28",{"name":5,"class":6},12]