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or recent use of any biologic agent within the following washout periods: etanercept \\&lt;28 days; infliximab and adalimumab \\&lt;60 days; golimumab \\&lt; 90 days; anti-IL-12\u002Fanti-IL-23 or anti-IL-23p19 antibody drugs \\&lt;6 months; or other anti-psoriatic therapy not listed herein within its 5 half-lives prior to randomization\n* A history of inflammatory bowel disease or other serious autoimmune disease\n* Previously diagnosed with serious mental illness such as anxiety, depression or suicidal tendency","ALL","18 Years","75 Years",{"count":283,"type":284},200,"ESTIMATED","INTERVENTIONAL",[287],"PHASE2","This study is a randomized, double-blind phase 2 clinical trial aimed at exploring the efficacy, safety, and immunogenicity of HB0017 injection with different dosing regimens in the treatment of moderate to severe plaque psoriasis in subjects",[290],"Psoriasis (PsO)",[25,292,293],"psoriasis","longer dose 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