[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100421609":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":42,"locations":48,"responsibleParty":65,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":32,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":50,"whyStopped":32,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"The Mind Research Network","OTHER",[8,15,21],{"label":9,"type":10,"description":11,"interventionNames":12},"MI with tACS","EXPERIMENTAL","Motivational interviewing with concurrent active stimulation",[13,14],"Device: High-density transcranial alternating current stimulation","Behavioral: Motivational interviewing",{"label":16,"type":17,"description":18,"interventionNames":19},"MI with sham","SHAM_COMPARATOR","Motivational interviewing with concurrent sham stimulation",[20,14],"Device: Sham stimulation",{"label":22,"type":23,"description":24,"interventionNames":25},"MI-only","ACTIVE_COMPARATOR","Motivational interviewing only, delayed treatment control",[14],[27,33,37],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","High-density transcranial alternating current stimulation","High-density electrode configuration with transcranial alternating current stimulation in the beta (15-40Hz) frequency range",[9],null,{"type":28,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"Sham stimulation","High-density electrode configuration with sham stimulation",[16],{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":32},"BEHAVIORAL","Motivational interviewing","Motivational interviewing session focused on alcohol use, approximately 30 minutes in length",[16,9,22],[43],{"name":44,"role":45,"phone":46,"phoneExt":32,"email":47},"Jon M Houck, PhD","CONTACT","(505) 925-2372","brainstim@mrn.org",[49],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Albuquerque","New Mexico","87106","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-106.65114,35.08449,{"lat":60,"lon":59},[63],{"name":44,"role":45,"phone":64,"phoneExt":32,"email":47},"505-925-2372",{"type":66,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[68],{"name":69,"class":70},"National Institute of General Medical Sciences (NIGMS)","NIH","100421609","phase-2-a-pilot-study-of-non-invasive-brain-stimulation-to-boost-the-efficacy-of-psychotherapy-in-a-community-sample-of-people-who-drink-alcohol-100421609",false,"NCT04770025","A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol","Transcranial Alternating Current Stimulation to Boost the Efficacy of Motivational Interviewing","tACS-MI","Inclusion criteria:\n\n* Self-identify as having problem drinking\n* Right-handed\n* Age 21-60 years\n* AUDIT score indicating risky drinking\n\nExclusion criteria:\n\n* Left-handed or ambidextrous\n* Currently engaged in treatment for alcohol use disorder\n* Receiving treatment for alcohol use disorder within the prior 12 months\n* History of brain injury or neurological diagnosis\n* Evidence of current psychosis\n* Past-year substance use disorder other than alcohol, marijuana, or nicotine\n* Current or history of severe alcohol withdrawal\n* MRI\u002FtACS contraindications including pregnancy\n* Impaired hearing (psychotherapy using American Sign Language is not possible within the scope of the proposed study)\n* Insufficient corrected visual acuity to complete the assessment instruments\n* Unable to read\u002Fspeak English fluently\n* Unable to provide valid informed consent",true,"ALL","21 Years","60 Years",{"count":84,"type":85},75,"ESTIMATED","INTERVENTIONAL",[88],"PHASE2","The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during motivational interviewing (MI) sessions with participants who drink at above the low-risk level. Participants will be randomized to receive either MI with active stimulation, MI with sham stimulation, or a delayed treatment group that receives MI with no stimulation. Measures will include brain imaging, alcohol use, cannabis use, risk-taking behavior, emotions, and others. Participants who are randomized to the delayed-treatment group will not receive brain imaging.",[91],"Alcohol Use Disorder",[91,93,94,95],"Motivational Interviewing","Transcranial Electrical Stimulation","Alcohol Drinking","2025-05-06",{"date":98,"type":99},"2025-05-08","ACTUAL",{"date":101,"type":99},"2020-09-01",{"date":103,"type":85},"2026-02-28",{"name":5,"class":6},1]