[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645418":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":49,"collaborators":24,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":24,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":73,"whyStopped":24,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Nantes University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Diprostene","EXPERIMENTAL","Supracapsular nerve block: injection of 10 mL of 1% lidocaine (2 mL along the needle path and 8 mL around the nerve), followed by an injection of 1 mL of DIPROSTENE®.\n\nIntra-articular injection: injection of 2 mL of 1% lidocaine along the needle path and 1 mL of KENACORT RETARD® 40 mg.",[13],"Drug: Diprostene",{"label":15,"type":16,"description":17,"interventionNames":18},"Saline Solution","PLACEBO_COMPARATOR","Suprascapular nerve block: Inject 2 mL of 1% lidocaine along the needle path, followed by 9 mL of normal saline.\n\nIntra-articular injection: injection of 2 mL of 1% lidocaine along the needle path and 1 mL of KENACORT RETARD® 40 mg.",[19],"Drug: Saline (0.9% NaCl)",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"DRUG",[9],null,{"type":22,"name":26,"description":17,"armGroupLabels":27,"otherNames":24},"Saline (0.9% NaCl)",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Paul ARNOLFO Paul, PH","CONTACT","02 44 76 81 79","Paul.arnolfo@chu-nantes.fr",[35],{"facility":36,"status":24,"city":37,"state":24,"zip":24,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"CHU de Nantes","Nantes","France","FR",{"type":41,"coordinates":42},"Point",[43,44],-1.55336,47.21725,{"lat":44,"lon":43},[47],{"name":48,"role":31,"phone":32,"phoneExt":24,"email":33},"Paul Arnolfo, PH",{"type":50,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100645418","phase-2-a-pilot-superiority-study-comparing-the-efficacy-of-a-combination-of-a-glenohumeral-intra-articular-injection-with-a-suprascapular-nerve-block-versus-a-glenohumeral-intra-articular-corticosteroid-injection-in-retractile-capsulitis-100645418",false,"NCT07680504","A Pilot Superiority Study Comparing the Efficacy of a Combination of a Glenohumeral Intra-articular Injection With a Suprascapular Nerve Block Versus a Glenohumeral Intra-articular Corticosteroid Injection in Retractile Capsulitis","EBLOUIR","Inclusion Criteria:\n\n* Patients with shoulder pain and stiffness that has persisted for at least 2 months but less than 12 months, with a loss of passive range of motion in at least 2 planes (lateral rotation, medial rotation, abduction, forward flexion) of at least 30 degrees compared to the contralateral side\n* Patients between the ages of 18 and 65\n* Patients enrolled in a social security program\n\nExclusion Criteria:\n\n* \\- Corticosteroid injection into the affected shoulder \\\u003C 4 months ago\n* History of any surgery on the affected shoulder within the past 12 months\n* Patients with a neuromuscular condition (neurological deficit) or shoulder condition (arthropathy) that could interfere with the assessment of the primary endpoint\n* Signs or risk of infection (bacterial-like infection and\u002For fever and\u002For antibiotic use)\n* Poor skin condition of the affected shoulder\n* Anticoagulation with VKAs or anti-Xa agents, or active bleeding disorder or one in remission for less than 5 years (malignant hematologic disorders, myelodysplasia, autoimmune thrombocytopenia) or chemotherapy (antiplatelet agents permitted except prasugrel and clopidogrel)\\*\n* Uncontrolled hypertension,\n* Decompensated diabetes or diabetes at risk of decompensation,\n* Contraindications to diprosten, Kenacort, or lidocaine\n* Psychiatric conditions that may be exacerbated by corticosteroids\n* Pregnant or breastfeeding women, or women who refuse to use effective contraception\n* Individuals belonging to a vulnerable group as defined by Regulation (EU) No. 536\u002F2014 and French law (See section 4.4 of the protocol) - - Patients unable to comply with the protocol requirements (see Section 4.4 of the protocol)\n* Patients participating in another clinical research protocol involving a drug or medical device\n* Patients who refuse to participate in the study","ALL","18 Years","65 Years",{"count":62,"type":63},38,"ESTIMATED","INTERVENTIONAL",[66],"PHASE2","Drug Trial\n\n* Single-center\n* Exploratory trial\n* Controlled\n* Randomized\n* Double-blind\n* Prospective\n\nObjective is to compare improvements in shoulder function at 3 months between the group receiving an intra-articular injection combined with a suprascapular nerve block and the group receiving an intra-articular injection combined with a placebo block 19 patients in the Experimental Group (block with corticosteroid and intra-articular injection on Day 0) 19 patients in the Control Group (block with saline and intra-articular injection on Day 0)\n\n* Total duration: 36 months\n* Recruitment period: 24 months\n* Treatment duration per patient: 2 ultrasound-guided procedures on Day 0\n* Follow-up duration per patient: 12 months after the procedure\n\nAt J0 : Under ultrasound guidance, inject 2 mL of lidocaine into the notch, then:\n\n* Experimental Group: 8 mL of 1% lidocaine into the notch with 1 mL of betamethasone,\n* Control Group: 9 mL of saline into the notch.\n\nDuring these consultations, M1, M3, M6 et M12 , the following examinations will be performed:\n\n* Clinical examination of the painful shoulder, including measurement of range of motion\n* Visual Analog Scale (VAS) for pain\n* Quick Dash, OSS, and SPADI self-report questionnaires completed by the patient\n* Recording of complications\n* Questions about returning to work",[69],"Retractile Capsulitis",[71,72],"suprascapular nerve block","intra-articular injection","NOT_YET_RECRUITING","2026-06-25",{"date":76,"type":77},"2026-07-02","ACTUAL",{"date":74,"type":63},{"date":80,"type":63},"2029-06-25",{"name":5,"class":6},1]