[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100501264":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":59,"collaborators":26,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":26,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Magnesium Group","EXPERIMENTAL","Subjects having urology surgery per standard of care will receive intravenous magnesium during the surgery.",[13],"Drug: Magnesium",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","Subjects having urology surgery per standard of care will receive intravenous placebo during the surgery.",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Magnesium","Intravenous infusion, load 50 mg\u002FKg with infusion of 15 mg\u002FKg\u002Fhour",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo","Equivalent volume of normal saline",[15],[32],{"name":33,"affiliation":5,"role":34},"Gregory Nuttall, MD","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Tami Krpata","CONTACT","507-422-5768","krpata.tami@mayo.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Mayo Clinic in Minnesota","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-92.4699,44.02163,{"lat":54,"lon":53},[57],{"name":58,"role":38,"phone":26,"phoneExt":26,"email":26},"Holly Carlson",{"type":34,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Gregory A Nuttall","Principal Investigator","100501264","phase-2-a-study-of-magnesium-and-bladder-spasms-following-ambulatory-urologic-procedures-100501264",false,"NCT05806996","A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures","Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures","Inclusion Criteria:\n\n\\- Be undergoing a bladder invasive procedure with or without planned urinary catheter on Mayo Clinic Gonda 7 Outpatient Procedure Center.\n\nExclusion Criteria:\n\n* Are unable to grant informed consent or comply with study procedure.\n* Allergy or known sensitivity to magnesium or Renacidin.\n* Expected or high risk of bladder extravasation.\n* Ongoing atrial fibrillation prior to surgery.\n* Are undergoing emergency surgery.\n* Are pregnant.\n* Known hypermagnesemia.\n* Patients with neuromuscular weakness (e.g., Myasthenia gravis) due to magnesium's muscle weakening effect.\n* Patients with myocardial compromise or cardiac conduction defects because of magnesium's anti-inotropic effects.\n* Patients with renal insufficiency, glomerular filtration rate less than 30, since Magnesium is eliminated by the kidneys resulting in exaggerated rise in serum magnesium.\n* Patients with concomitant use of a calcium channel blocker since magnesium sulfate could act synergistically to suppress muscular contractility.","ALL","18 Years",{"count":72,"type":73},120,"ESTIMATED","INTERVENTIONAL",[76],"PHASE2","This research is being done to find out whether intravenous magnesium is effective in the treatment of bladder spasms after urologic surgery.",[79],"Bladder Spasms","2026-06-25",{"date":82,"type":83},"2026-06-29","ACTUAL",{"date":85,"type":83},"2023-07-31",{"date":87,"type":73},"2026-12-31",{"name":5,"class":6},1]