[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555411":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":34,"centralContacts":34,"locations":39,"responsibleParty":58,"collaborators":60,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":34,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":34,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":34,"overallStatus":42,"whyStopped":34,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"CSPC Ouyi Pharmaceutical Co., Ltd.","INDUSTRY",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"SYHX1901-A","EXPERIMENTAL","Participants in this group will receive dose A of SYHX1901 orally once daily (QD) for 52 weeks",[13],"Drug: SYHX1901",{"label":15,"type":10,"description":16,"interventionNames":17},"SYHX1901-B","Participants in this group will receive dose B of SYHX1901 orally QD for 52 weeks",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"SYHX1901-C","articipants in this group will receive dose C of SYHX1901 orally QD for 52 weeks",[13],{"label":23,"type":24,"description":25,"interventionNames":26},"Placebo followed by dose C of SYHX1901","PLACEBO_COMPARATOR","Participants in this group will receive placebo orally QD for 24 weeks followed by dose C of SYHX1901 orally QD for 28 weeks.",[13,27],"Drug: placebo",[29,35],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DRUG","SYHX1901","SYHX1901 tablet",[23,9,15,19],null,{"type":30,"name":36,"description":37,"armGroupLabels":38,"otherNames":34},"placebo","Oral tablet",[23],[40],{"facility":41,"status":42,"city":43,"state":34,"zip":34,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Clinical Trials Information Group","RECRUITING","Shijiazhuang","China","CN",{"type":47,"coordinates":48},"Point",[49,50],114.47861,38.04139,{"lat":50,"lon":49},[53],{"name":54,"role":55,"phone":56,"phoneExt":34,"email":57},"Clinical Trials Information Group officer","CONTACT","86-0311-69085587","ctr-contact@cspc.cn",{"type":59,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR",[61],{"name":62,"class":63},"Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd.","UNKNOWN","100555411","phase-2-a-study-to-evaluate-the-efficacy-and-safety-of-syhx1901-tablet-in-non-segmental-vitiligo-patients-100555411",false,"NCT06511739","A Study to Evaluate the Efficacy and Safety of SYHX1901 Tablet in Non-segmental Vitiligo Patients","A Phase 2 Randomized Double-blind Placebo-controlled Study to Evaluate the Efficacy and Safety of SYHX1901 Tablet in Non-segmental Vitiligo Patients","Inclusion Criteria:\n\n1. Willing to sign an ICF, able to comprehend and comply with the study procedures.\n2. Male or female subjects aged 18 to 65，inclusive.\n3. Subjects with a clinical diagnosis of non-segmental vitiligo.\n4. Agree to stop all other treatments for vitiligo during the study period.\n5. Women of child-bearing potential must have a negative serum pregnancy test within 3 days prior to the first study agent administration.\n\nExclusion Criteria:\n\n1. Diagnosed as other active depigmentation disease.\n2. At screening or baseline visits, subject exhibits active inflammatory dermatologic disease or symptoms that in the opinion of investigators would interfere of vitiligo evaluation or response to treatment.\n3. Uncontrolled thyroid function at screening as determined by the investigator.\n4. Use of permanent depigmentation treatment or skin grafts.\n5. Use of phototherapy, topical or systemic treatments within certain time frame prior to Day1.\n6. Have active bacterial\u002Fvirus\u002Fother pathogens infection or infestation that require medical intervention.\n7. Have progressive or uncontrolled systemic disease, or other concomitant chronic disease that the investigators believe unsuitable to participate the study.\n8. History of alcohol and drug abuse within one year prior to screening; History of neurological or mental disorders with diagnosis records, such as severe depression, suicidal tendencies, epilepsy, dementia, etc.\n9. Have any other reasons determined by the investigator that the subject is not eligible for the study.","ALL","18 Years","65 Years",{"count":75,"type":76},144,"ESTIMATED","INTERVENTIONAL",[79],"PHASE2","A 52-Week Study of SYHX1901 tablet in Adults with non-segmental vitiligo.",[82],"Non-segmental Vitiligo","2024-07-15",{"date":85,"type":86},"2024-07-22","ACTUAL",{"date":88,"type":86},"2024-05-27",{"date":90,"type":76},"2025-10-01",{"name":5,"class":6},1]