[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522297":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":243,"collaborators":18,"id":245,"slug":246,"hasResults":247,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":18,"eligibilityCriteria":251,"healthyVolunteers":247,"sex":252,"minAge":253,"maxAge":254,"enrollmentInfo":255,"targetDuration":18,"studyType":258,"phases":259,"briefSummary":261,"conditions":262,"keywords":18,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":273},{"fullName":5,"class":6},"Panafina, Inc.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RABI-767 plus Standard-of-Care","EXPERIMENTAL","Single-dose 125 mg RABI-767 plus standard-of-care",[13],"Drug: RABI-767",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard-of-Care Only","NO_INTERVENTION","No Intervention, Standard-of-Care Only",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DRUG","RABI-767","125 mg single-dose given by endoscopic-ultrasound (EUS) guided peripancreatic injection.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Kelly Abernathy","CONTACT","9194609500","kabernathy@arrivobio.com",[32,50,64,77,90,102,115,126,139,152,165,177,192,205,218,230],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"University of Arkansas for Medical Sciences","RECRUITING","Little Rock","Arkansas","72205","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-92.28959,34.74648,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":18,"email":18},"Clinical Research Coordinator","501-526-4860",{"facility":51,"status":34,"city":52,"state":53,"zip":54,"country":38,"countryCode":39,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Keck Hospital of USC and LA County Hospital","Los Angeles","California","90033",{"type":41,"coordinates":56},[57,58],-118.24368,34.05223,{"lat":58,"lon":57},[61,62],{"name":48,"role":28,"phone":18,"phoneExt":18,"email":18},{"name":18,"role":28,"phone":63,"phoneExt":18,"email":18},"323-409-6939",{"facility":65,"status":34,"city":66,"state":67,"zip":68,"country":38,"countryCode":39,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"University of Colorado Anschutz Medical Campus","Aurora","Colorado","80045",{"type":41,"coordinates":70},[71,72],-104.83192,39.72943,{"lat":72,"lon":71},[75],{"name":48,"role":28,"phone":76,"phoneExt":18,"email":18},"303-724-1871",{"facility":78,"status":34,"city":79,"state":80,"zip":81,"country":38,"countryCode":39,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"University of Florida Health","Gainesville","Florida","32608",{"type":41,"coordinates":83},[84,85],-82.32483,29.65163,{"lat":85,"lon":84},[88],{"name":48,"role":28,"phone":89,"phoneExt":18,"email":18},"352-273-9483",{"facility":91,"status":34,"city":92,"state":80,"zip":93,"country":38,"countryCode":39,"cosmosGeoPoint":94,"geoPoint":98,"contacts":99},"Orlando Health","Orlando","32806",{"type":41,"coordinates":95},[96,97],-81.37924,28.53834,{"lat":97,"lon":96},[100],{"name":48,"role":28,"phone":101,"phoneExt":18,"email":18},"321-841-6649",{"facility":103,"status":34,"city":104,"state":105,"zip":106,"country":38,"countryCode":39,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"UI Health, University of Illinois Chicago Hospital Health Sciences System","Chicago","Illinois","60612",{"type":41,"coordinates":108},[109,110],-87.65005,41.85003,{"lat":110,"lon":109},[113],{"name":48,"role":28,"phone":114,"phoneExt":18,"email":18},"630-518-5456",{"facility":116,"status":117,"city":118,"state":119,"zip":120,"country":38,"countryCode":39,"cosmosGeoPoint":121,"geoPoint":125,"contacts":18},"Indiana University Health University Hospital","WITHDRAWN","Indianapolis","Indiana","46202",{"type":41,"coordinates":122},[123,124],-86.15804,39.76838,{"lat":124,"lon":123},{"facility":127,"status":34,"city":128,"state":129,"zip":130,"country":38,"countryCode":39,"cosmosGeoPoint":131,"geoPoint":135,"contacts":136},"Johns Hopkins Hospital","Baltimore","Maryland","21287",{"type":41,"coordinates":132},[133,134],-76.61219,39.29038,{"lat":134,"lon":133},[137],{"name":48,"role":28,"phone":138,"phoneExt":18,"email":18},"410-614-6708",{"facility":140,"status":34,"city":141,"state":142,"zip":143,"country":38,"countryCode":39,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"Henry Ford Hospital","Detroit","Michigan","48202",{"type":41,"coordinates":145},[146,147],-83.04575,42.33143,{"lat":147,"lon":146},[150],{"name":48,"role":28,"phone":151,"phoneExt":18,"email":18},"313-746-8215",{"facility":153,"status":34,"city":154,"state":155,"zip":156,"country":38,"countryCode":39,"cosmosGeoPoint":157,"geoPoint":161,"contacts":162},"Dartmouth Hitchcock Medical Center","Lebanon","New Hampshire","03756",{"type":41,"coordinates":158},[159,160],-72.25176,43.64229,{"lat":160,"lon":159},[163],{"name":48,"role":28,"phone":164,"phoneExt":18,"email":18},"603-653-3651",{"facility":166,"status":34,"city":167,"state":167,"zip":168,"country":38,"countryCode":39,"cosmosGeoPoint":169,"geoPoint":173,"contacts":174},"NYU Langone Medical Center","New York","10016",{"type":41,"coordinates":170},[171,172],-74.00597,40.71427,{"lat":172,"lon":171},[175],{"name":48,"role":28,"phone":176,"phoneExt":18,"email":18},"212-263-3095",{"facility":178,"status":34,"city":179,"state":180,"zip":181,"country":182,"countryCode":183,"cosmosGeoPoint":184,"geoPoint":188,"contacts":189},"Lisie Hospital","Kochi","Kerala","682018","India","IN",{"type":41,"coordinates":185},[186,187],76.26022,9.93988,{"lat":187,"lon":186},[190],{"name":48,"role":28,"phone":191,"phoneExt":18,"email":18},"+91 859-095-8869",{"facility":193,"status":34,"city":194,"state":195,"zip":196,"country":182,"countryCode":183,"cosmosGeoPoint":197,"geoPoint":201,"contacts":202},"Christian Medical College (CMC) Vellore, Ranipet Campus","Vellore","TamiNadu","632517",{"type":41,"coordinates":198},[199,200],79.13255,12.9184,{"lat":200,"lon":199},[203],{"name":48,"role":28,"phone":204,"phoneExt":18,"email":18},"+91 987-249-3649",{"facility":206,"status":207,"city":208,"state":18,"zip":18,"country":182,"countryCode":183,"cosmosGeoPoint":209,"geoPoint":213,"contacts":214},"Postgraduate Institute of Medical Education and Research","NOT_YET_RECRUITING","Chandigarh",{"type":41,"coordinates":210},[211,212],76.7884,30.73629,{"lat":212,"lon":211},[215,216],{"name":48,"role":28,"phone":18,"phoneExt":18,"email":18},{"name":18,"role":28,"phone":217,"phoneExt":18,"email":18},"(+91) 9015143233",{"facility":219,"status":34,"city":220,"state":18,"zip":221,"country":182,"countryCode":183,"cosmosGeoPoint":222,"geoPoint":226,"contacts":227},"All India Institute of Medical Sciences","Delhi","110029",{"type":41,"coordinates":223},[224,225],77.23149,28.65195,{"lat":225,"lon":224},[228],{"name":48,"role":28,"phone":229,"phoneExt":18,"email":18},"+91 941-160-2782",{"facility":231,"status":34,"city":232,"state":18,"zip":233,"country":182,"countryCode":183,"cosmosGeoPoint":234,"geoPoint":238,"contacts":239},"Govind Ballabh Pant Institute of Postgraduate Medical Education and Research","New Delhi","110002",{"type":41,"coordinates":235},[236,237],77.2148,28.62137,{"lat":237,"lon":236},[240,241],{"name":48,"role":28,"phone":18,"phoneExt":18,"email":18},{"name":18,"role":28,"phone":242,"phoneExt":18,"email":18},"+91 6205261118",{"type":244,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100522297","phase-2-a-study-to-evaluate-the-safety-and-efficacy-of-a-single-dose-of-rabi-767-in-participants-with-acute-pancreatitis-100522297",false,"NCT06080789","A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis","A Phase 2a, Multi-Center, Randomized, Open-Label Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 Administered by Endoscopic Ultrasound-Guided Peripancreatic Injection Plus Standard-of-Care Versus Standard-of-Care Only in Participants With Predicted Severe Acute Pancreatitis","Key Inclusion Criteria:\n\n* Diagnosis of acute pancreatitis\n* Predicted severe acute pancreatitis, based on protocol defined criteria\n* Lack of clinically meaningful improvement from status at admission, at the discretion of Investigator, at the time of randomization\n* Suitable for EUS-guided study drug administration procedure\n* Contrast-enhanced computed tomography (CECT) or magnetic resonance imaging (MRI) of the abdomen\u002Fpancreas available for the evaluation of exclusion criteria\n\nKey Exclusion Criteria:\n\n* Confirmed severe acute pancreatitis as defined by the Revised Atlanta Classification of Acute Pancreatitis (ie, Persistent \\[\\> 48 hours\\] organ failure, per Modified Marshall Score), prior to randomization\n* Anticipated discharge from hospital within 48 hours of randomization\n* More than 30% pancreatic necrosis on screening CECT or MRI\n* History of previous pancreatic necrosis, including necrosectomy\n* History of calcific chronic pancreatitis\n* Evidence of cholangitis","ALL","18 Years","85 Years",{"count":256,"type":257},36,"ESTIMATED","INTERVENTIONAL",[260],"PHASE2","The goal of this clinical trial is to test the safety and effectiveness of a single dose of RABI-767 given by endoscopic ultrasound (EUS) guided peripancreatic injection in participants with predicted severe acute pancreatitis.\n\nThe main question the study aims to answer is:\n\n• Is a single-dose of RABI-767 given by EUS-guided peripancreatic injection safe in patients with predicted severe acute pancreatitis.\n\nThe study also aims to answer:\n\n• Is a single-dose of RABI-767 given by EUS-guided peripancreatic injection effective in treating patients with predicted severe acute pancreatitis.\n\nStudy participants will be randomly assigned (like the flip of a coin) to receive a single dose of RABI-767 plus supportive care or supportive care only.\n\nThe study sponsor will compare safety and efficacy data collected from participants who receive RABI-767 to participants who receive supportive care only to test if RABI-767 is safe and effective.",[263],"Acute Pancreatitis","2026-05-26",{"date":266,"type":267},"2026-05-28","ACTUAL",{"date":269,"type":267},"2024-06-28",{"date":271,"type":257},"2026-12",{"name":5,"class":6},16]