[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577686":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":62,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Shaheed Mohtarma Benazir Bhutto Institue of Trauma","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Xylometazoline Group","EXPERIMENTAL","Participants in this group will receive xylometazoline nasal drops before nasotracheal intubation",[13],"Drug: 0.1% xylometazoline nasal drops",{"label":15,"type":16,"description":17,"interventionNames":18},"Adrenaline Group","ACTIVE_COMPARATOR","Participants in this group will recieve adrenaline nasal packing before nasotracheal intubation",[19],"Drug: Adrenaline nasal pack",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","0.1% xylometazoline nasal drops","Xylometazoline is direct acting, non selective, adrenergic agonist binding with alpha 1\\&2 receptors, used for vasoconstriction to decrease nasal bleeding.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Adrenaline nasal pack","Adrenaline is direct acting, non selective, adrenergic agonist binding with alpha and beta receptors both, used for vasoconstriction to decrease nasal bleeding.",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Dr Sidra Javed Consultant Anaesthetist, MBBS, FCPS, PAIN FELLOW","CONTACT","+92333 2474831","sidra_dow@yahoo.com",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},"Dr Mirza Shahzad Baig Consultant Anaesthetist, MBBS, MCPS, FCPS","+923346441539","drshahzadbaig@hotmail.com",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Shaheed Mohtarma Benazir Bhutto Institute of Trauma","RECRUITING","Karachi","Sindh","Pakistan","PK",{"type":50,"coordinates":51},"Point",[52,53],67.0104,24.8608,{"lat":53,"lon":52},[56,59],{"name":57,"role":58,"phone":26,"phoneExt":26,"email":26},"Iqra Ashraf, MBBS, FCPS TRAINEE","PRINCIPAL_INVESTIGATOR",{"name":60,"role":61,"phone":26,"phoneExt":26,"email":26},"Sidra Tahir, MBBS, FCPS TRAINEE","SUB_INVESTIGATOR",{"type":58,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"IQRA ASHRAF","Principal Investigator","100577686","phase-2-adrenaline-nasal-pack-vs-xylometazoline-nasal-drops-during-nasotracheal-intubation-100577686",false,"NCT06801522","Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation","Comparison of the Efficacy of Adrenaline Nasal Pack and Xylometazoline Nasal Drops in Decreasing Nasal Bleeding During Nasotracheal Intubation","Inclusion Criteria:\n\n* ASA 1 and 2\n* Age group between 18-60 years\n* Mallampati score 1 and 2\n* Either gender\n* Participants who undergo elective oromaxillofacial surgery\n\nExclusion Criteria:\n\n* Lack of consent\n* Participants with anticipated difficult airway\n* Participants receiving anticoagulant therapy\n* History of nasal abnormality (nasal surgery, trauma, polyp, obstruction)\n* History of repeated epistaxis\n* History of uncontrolled hypertension, diabetes, pregnancy, and any other cardiac or cerebral events.","ALL","18 Years","60 Years",{"count":76,"type":77},70,"ESTIMATED","INTERVENTIONAL",[80,81],"PHASE2","PHASE3","The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries.\n\nThe main question aim to answer is xylometazoline nasal drops better than adrenaline nasal packing in terms of nasal bleeding during nasotracheal intubation. Researchers are comparing 2 groups of participants.\n\nParticipants in group Xylometazoline are receiving 0.1% xylometaxoline nasal drops.\n\nParticipants in group Adrenaline are receiving adrenaline nasal packing.",[84,85],"Nasal Bleeding","Nasotracheal Intubation",[87],"Nasal bleeding, Nasotracheal intubation, adrenaline pack, xylometazoline nasal drops","2025-01-24",{"date":90,"type":91},"2025-01-30","ACTUAL",{"date":93,"type":91},"2024-12-01",{"date":95,"type":77},"2025-05",{"name":5,"class":6},1]