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Korea",{"type":57,"coordinates":677},[678,679],129.03004,35.10168,{"lat":679,"lon":678},{"facility":682,"status":50,"city":683,"state":684,"zip":685,"country":675,"countryCode":34,"cosmosGeoPoint":34,"geoPoint":34,"contacts":34},"Keimyung University Dongsan Hospital \u002FID# 272455","Daegu","Gyeongsangbuk-do","42601",{"facility":687,"status":50,"city":688,"state":689,"zip":690,"country":675,"countryCode":34,"cosmosGeoPoint":691,"geoPoint":695,"contacts":34},"Seoul National University Hospital \u002FID# 271331","Seoul","Seoul Teugbyeolsi","03080",{"type":57,"coordinates":692},[693,694],126.9784,37.566,{"lat":694,"lon":693},{"facility":697,"status":50,"city":688,"state":689,"zip":698,"country":675,"countryCode":34,"cosmosGeoPoint":699,"geoPoint":701,"contacts":34},"SMG-SNU Boramae Medical Center \u002FID# 271227","07061",{"type":57,"coordinates":700},[693,694],{"lat":694,"lon":693},{"facility":703,"status":50,"city":688,"state":689,"zip":704,"country":675,"countryCode":34,"cosmosGeoPoint":705,"geoPoint":707,"contacts":34},"Hallym University Kangnam Sacred Heart Hospital \u002FID# 271329","07441",{"type":57,"coordinates":706},[693,694],{"lat":694,"lon":693},{"facility":709,"status":50,"city":710,"state":711,"zip":712,"country":713,"countryCode":714,"cosmosGeoPoint":715,"geoPoint":719,"contacts":34},"Hospital Universitari de Bellvitge \u002FID# 270489","L'Hospitalet de Llobregat","Barcelona","08907","Spain","ES",{"type":57,"coordinates":716},[717,718],2.10028,41.35967,{"lat":718,"lon":717},{"facility":721,"status":50,"city":711,"state":34,"zip":722,"country":713,"countryCode":714,"cosmosGeoPoint":723,"geoPoint":727,"contacts":34},"Fundacio Puigvert \u002FID# 270491","08025",{"type":57,"coordinates":724},[725,726],2.15899,41.38879,{"lat":726,"lon":725},{"facility":729,"status":50,"city":730,"state":34,"zip":731,"country":713,"countryCode":714,"cosmosGeoPoint":732,"geoPoint":736,"contacts":34},"Hospital Universitario Virgen de las Nieves \u002FID# 270918","Granada","18014",{"type":57,"coordinates":733},[734,735],-3.60667,37.18817,{"lat":735,"lon":734},{"facility":738,"status":50,"city":739,"state":34,"zip":740,"country":713,"countryCode":714,"cosmosGeoPoint":741,"geoPoint":745,"contacts":34},"Hospital Universitario Fundacion Jimenez Diaz \u002FID# 270485","Madrid","28040",{"type":57,"coordinates":742},[743,744],-3.70256,40.4165,{"lat":744,"lon":743},{"facility":747,"status":50,"city":739,"state":34,"zip":748,"country":713,"countryCode":714,"cosmosGeoPoint":749,"geoPoint":751,"contacts":34},"Hospital Universitario 12 de Octubre \u002FID# 270829","28041",{"type":57,"coordinates":750},[743,744],{"lat":744,"lon":743},{"facility":753,"status":50,"city":754,"state":34,"zip":755,"country":713,"countryCode":714,"cosmosGeoPoint":756,"geoPoint":760,"contacts":34},"Hospital Clínico Universitario de Valencia \u002FID# 270837","Valencia","46010",{"type":57,"coordinates":757},[758,759],-0.37966,39.47391,{"lat":759,"lon":758},{"type":762,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR","100585453","phase-2-anchor-study-a-study-to-assess-the-safety-and-efficacy-of-abbv-cls-628-in-adult-participants-with-autosomal-dominant-polycystic-kidney-disease-adpkd-100585453",false,"NCT06902558","ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)","A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of ABBV-CLS-628 in Adult Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)","ANCHOR","Inclusion Criteria:\n\n* Autosomal Dominant Polycystic Kidney Disease (ADPKD) Class 1C, 1D, or 1E based on the Mayo Clinic Imaging Classification of ADPKD.\n* Estimated glomerular filtration rate (eGFR) \\>= 30 mL\u002Fmin\u002F1.73 m\\^2 and \\\u003C 90 mL\u002Fmin\u002F1.73 m\\^2, using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation at Screening.\n\nExclusion Criteria:\n\n* Current interventions to treat ADPKD such as non-approved medications or lifestyle modifications.\n* Any exclusionary medical diseases, disorders, or conditions as described in the protocol.","ALL","18 Years","55 Years",{"count":775,"type":776},240,"ESTIMATED","INTERVENTIONAL",[779],"PHASE2","Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that causes fluid-filled cysts to develop in the kidneys. The purpose of this study is to assess the safety and efficacy of ABBV-CLS-628 for the treatment of ADPKD in adult participants.\n\nABBV-CLS-628 is an investigational drug being developed for the treatment of ADPKD. Participants are placed in 1 of 4 groups, called treatment arms. Each group receives a different treatment. There is a 1 in 4 chance that participants will be assigned to placebo. Around 240 adult participants with ADPKD will be enrolled at approximately 100 sites worldwide.\n\nParticipants will receive IntraVenous ABBV-CLS-628 or placebo every 4 weeks for 92 weeks. Participants will be followed for up to 15 weeks.\n\nThere may be higher treatment burden for participants in this trial compared to their standard of care . Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.",[782],"Autosomal Dominant Polycystic Kidney Disease",[784,31],"Autosomal Dominant Polycystic Kidney Disease (ADPKD)","2026-05-22",{"date":787,"type":788},"2026-05-26","ACTUAL",{"date":790,"type":788},"2025-06-09",{"date":792,"type":776},"2029-08",{"name":5,"class":6},75]