[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510325":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":38,"responsibleParty":56,"collaborators":59,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":18,"enrollmentInfo":72,"targetDuration":18,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"MemorialCare Health System","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard blood pressure control plus aspirin 81 mg","EXPERIMENTAL","Standardized postpartum blood pressure control Aspirin 81 mg by mouth x 1 week post-delivery",[13],"Drug: Aspirin 81Mg Ec Tab",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard blood pressure control","NO_INTERVENTION","Standardized postpartum blood pressure control",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DRUG","Aspirin 81Mg Ec Tab","Aspirin 81 mg 1 tablet by mouth. Participants randomized to receive aspirin in addition to standard blood pressure management will receive the study medication nightly at 20:00, with first dose initiated within 24 hours of delivery.",[9],[26],{"name":27,"affiliation":28,"role":29},"Megan C Oakes, MD MSCI","Miller Children's and Women's Hospital, Long Beach\u002F MemorialCare Medical Center","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","562-997-8510","moakes2@memorialcare.org",{"name":36,"role":32,"phone":33,"phoneExt":18,"email":37},"Ashten B Waks, MD MSPH","awaks@memorialcare.org",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Miller Children's and Women's Hospital, Long Beach\u002FMemorialCare Long Beach","RECRUITING","Long Beach","California","90740","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-118.18923,33.76696,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":33,"phoneExt":18,"email":34},"Megan Oakes, MD",{"type":29,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Megan Oakes","MD MSCI",[60],{"name":61,"class":6},"University of California, Irvine","100510325","phase-2-aspirin-for-postpartum-patients-with-preeclampsia-100510325",false,"NCT05924971","Aspirin for Postpartum Patients With Preeclampsia","Acetylsalicylic Acid for Postpartum Preeclampsia: A Pilot Randomized Trial","ASAPP","Inclusion Criteria:\n\n* Preeclampsia with severe features diagnosed during delivery admission, as defined by ACOG criteria.\n* Pre- and postnatal care provided by the Long Beach Memorial Ob\u002FGyn resident or Maternal-Fetal Medicine clinic.\n\nExclusion Criteria:\n\n* Patient age \\\u003C18 years old\n* Non-English or Non-Spanish speaking\n* Chronic hypertension diagnosed before 20 weeks' gestation\n* Known allergy, prior adverse reaction, or any medical condition in which aspirin is contraindicated (nasal polyps, gastric or duodenal ulcers, history of gastrointestinal bleeding, severe hepatic dysfunction)\n* Aspirin prescribed postpartum for any other medical condition\n* Bleeding disorder\n* Breastfeeding an infant with thrombocytopenia","FEMALE","18 Years",{"count":73,"type":74},86,"ESTIMATED","INTERVENTIONAL",[77],"PHASE2","The purpose of this research study is to evaluate the effect of low-dose aspirin on recovery from severe preeclampsia (a high blood pressure disorder of pregnancy) among women who have given birth. We hypothesize that taking aspirin for the first week after giving birth will enhance recovery from preeclampsia by decreasing the levels of a protein called soluble fms-like tyrosine kinase (sFlt-1), which is thought to be a main contributor to the development of preeclampsia, and speeding up return to a normal blood pressure.",[80],"Preeclampsia Postpartum",[82,83,84,85],"Preeclampsia","Postpartum","Aspirin","sFlt-1","2025-06-03",{"date":88,"type":89},"2025-06-06","ACTUAL",{"date":91,"type":89},"2023-07-26",{"date":93,"type":74},"2026-12",{"name":5,"class":6},1]