[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576047":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":37,"locations":43,"responsibleParty":76,"collaborators":32,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":32,"eligibilityCriteria":84,"healthyVolunteers":81,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":32,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":46,"whyStopped":32,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Emory University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Medrol","EXPERIMENTAL","The group will be given Medrol Dosepak in a tapered, low-dose manner, orally once a day.\n\nSubjects will be sent home with a pain journal where they will record their pain and nausea 3 times daily starting the day of surgery and the following 7 days along with their daily hydrocodone consumption. These journals will be collected at their 2-week post-op appointment which is scheduled ± 1 week. In this appointment, subjects will also be evaluated for complications.",[13,14],"Drug: medrol dosepak","Drug: HYDROcodone Oral Tablet",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard of Care","ACTIVE_COMPARATOR","Each subject will receive the standard pain regime of both surgeons. This includes a nerve block before surgery for pain prevention. While in surgery, the subject will receive 10 mg of dexamethasone intravenously. Post-surgery, each subject will be instructed to take vitamin C for nerve pain and vitamin D for bone healing. They will also be provided with a prescription of aspirin for deep vein thrombosis (DVT) prophylaxis, ondansetron (Zofran) for nausea, and Colace for constipation relief. Both groups will receive a prescription of 20 5 mg hydrocodone pills to be taken as needed for pain, 1 every 6 hours\n\nSubjects will be sent home with a pain journal where they will record their pain and nausea 3 times starting the day of surgery and the following 7 days along with their daily hydrocodone consumption. Journals will be collected at their 2-week post-op appointment which is scheduled ± 1 week. Subjects will also be evaluated for complications",[14],[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","medrol dosepak","Methylprednisolone is a corticosteroid with anti-inflammatory properties and immune suppression.\n\nThis study will utilize a 6-day Medrol Dosepak: a tapered low-dose corticosteroid course taken orally once a day. This includes 6 tablets on day 1 (24 mg), 5 tablets on day 2 (20 mg), 4 tablets on day 3 (16 mg), 3 tablets on day 4 (12 mg), 2 tablets on day 5 (8 mg) and 1 tablet on day 6 (4 mg).",[9],[27],"Methylprednisolone",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"HYDROcodone Oral Tablet","This study will utilize a prescription of 20 pills of hydrocodone, 5mg each, to be taken as needed for pain, 1 every 6 hours.",[9,16],null,[34],{"name":35,"affiliation":5,"role":36},"Rishin Kadakia, MD","PRINCIPAL_INVESTIGATOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},"Jason Bariteau, MD","CONTACT","404-778-3350","jason.bariteau@emory.edu",[44,64],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Emory Musculoskeletal Institute, Emory Orthopaedics & Spine Center","RECRUITING","Atlanta","Georgia","30329","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-84.38798,33.749,{"lat":56,"lon":55},[59,60,62],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},{"name":61,"role":36,"phone":32,"phoneExt":32,"email":32},"Jason Kadakia, MD",{"name":63,"role":36,"phone":32,"phoneExt":32,"email":32},"Rishin Bariteau, MD",{"facility":65,"status":46,"city":66,"state":48,"zip":67,"country":50,"countryCode":51,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Emory Sports Medicine Complex and Emory Orthopaedics and Spine Center","Johns Creek","30022",{"type":53,"coordinates":69},[70,71],-84.19858,34.02893,{"lat":71,"lon":70},[74],{"name":35,"role":40,"phone":41,"phoneExt":32,"email":75},"rishin.j.kadakia@emory.edu",{"type":36,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Jason Bariteau","Associate Professor","100576047","phase-2-assessment-of-medrol-dosepak-to-reduce-opioid-consumption-in-foot-and-ankle-surgical-patients-100576047",false,"NCT06780202","Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients","Inclusion Criteria:\n\n-Emory Orthopedic patients undergoing foot and ankle surgery\n\nExclusion Criteria:\n\n* Concurrent or significant injuries to other bones or organs\n* Local infections\n* History of alcohol or medical abuse, including prior opioid abuse\n* Smoking\n* History of severe heart disease, renal failure, liver dysfunction, active peptic ulcer disease, diabetes, rheumatoid arthritis, neurological or psychiatric diseases that could influence pain perception\n* Pre-existing immune suppression\n* Those deemed possibly non-compliant by the study team and,\n* All vulnerable populations (those unable to give consent, juveniles, pregnant women, prisoners, cognitively impaired and non-English speaking).","ALL","18 Years","95 Years",{"count":89,"type":90},180,"ESTIMATED","INTERVENTIONAL",[93],"PHASE2","This clinical trial aims to determine the effects of a 6-day low-dose methylprednisolone course on pain, nausea, and total opioid consumption in patients undergoing foot and ankle surgeries.\n\nThe secondary objective of the study is to determine and monitor the effects of the course on complications following surgery and patient-reported outcomes",[96,97,98],"Foot Injuries and Disorders","Ankle Injuries and Disorders","Achilles Tendon Injury",[100,101],"VAS scale: visual analog scale","Medrol Dosepak","2026-03-05",{"date":104,"type":105},"2026-03-09","ACTUAL",{"date":107,"type":105},"2025-01-27",{"date":109,"type":90},"2027-12",{"name":5,"class":6},2]