[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100356129":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":25,"studyType":82,"phases":83,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Genesis Athens Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants receiving PRP treatment","EXPERIMENTAL","Menopausal women minimum 45 years of age, receiving ovarian PRP treatment.",[13],"Biological: Autologous PRP intra ovarian infusion",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group: Participants receiving Platelet Free Plasma","PLACEBO_COMPARATOR","Women in menopause, 45-55 years old, treated with autologous PFP intra ovarian infusion.",[19],"Biological: Autologous PFP intra ovarian infusion",[21,26],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"BIOLOGICAL","Autologous PRP intra ovarian infusion",[9],null,{"type":22,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"Autologous PFP intra ovarian infusion",[15],[30],{"name":31,"affiliation":32,"role":33},"Agni Pantou, MD","Centre of Human Reproduction, Genesis Athens Clinic","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Mara Simopoulou, PhD","CONTACT","+306979234100","marasimopoulou@hotmail.com",{"name":31,"role":37,"phone":41,"phoneExt":25,"email":42},"+306974447702","agni.pantou@genesisathens.gr",[44],{"facility":45,"status":46,"city":47,"state":25,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Genesis AC","RECRUITING","Athens","15232","Greece","GR",{"type":52,"coordinates":53},"Point",[54,55],23.72784,37.98376,{"lat":55,"lon":54},[58,59,60],{"name":31,"role":37,"phone":25,"phoneExt":25,"email":42},{"name":31,"role":33,"phone":25,"phoneExt":25,"email":25},{"name":61,"role":33,"phone":25,"phoneExt":25,"email":25},"Konstantinos Pantos, MD,PhD",{"type":63,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[65],{"name":66,"class":6},"National and Kapodistrian University of Athens","100356129","phase-2-autologous-prp-intra-ovarian-infusion-to-restore-ovarian-function-in-menopausal-women-100356129",false,"NCT03916978","Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women","Investigating Reactivation of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in Menopausal Women","PRP","Inclusion Criteria:\n\n* Age between 45-55 years old\n* Amenorrhea for at least 12 months\n* Discontinuation of any complementary\u002Fadjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.\n* Willing to comply with study requirements\n\nExclusion Criteria:\n\n* Any pathological disorder related to reproductive system anatomy\n* Previous POI diagnosis\n* Abnormal karyotype\n* Endometriosis\n* Adenomyosis\n* Fibroids and adhesions\n* Infections in reproductive system\n* Current or previous diagnosis of reproductive system cancer\n* History of familiar cancer in reproductive system\n* Severe male factor infertility\n* Prior referral for PGT\n* Ovarian inaccessibility\n* Endocrinological disorders (Hypothalamus-Pituitary disorders, thyroid dysfunction, diabetes mellitus, metabolic syndrome)\n* BMI\\>30 kg\u002Fm2 or BMI\\\u003C18.5 kg\u002Fm2\n* Systematic autoimmune disorders",true,"FEMALE","45 Years","55 Years",{"count":80,"type":81},100,"ESTIMATED","INTERVENTIONAL",[84,85],"PHASE2","PHASE3","Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.",[88,89,90,91],"Infertility, Female","Anovulatory Infertility","Menopause","Amenorrhea",[93,94],"Ovarian rejuvenation","Ovarian reactivation; ovulation","2024-12-20",{"date":97,"type":98},"2024-12-27","ACTUAL",{"date":100,"type":98},"2019-05-21",{"date":102,"type":81},"2026-07-30",{"name":5,"class":6},1]