[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627369":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":38,"responsibleParty":54,"collaborators":18,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":18,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":18,"maxAge":66,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":83,"whyStopped":18,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"New York Medical College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Betamethasone arm","EXPERIMENTAL","Infants who meet clinical criteria will receive postnatal betamethasone",[13],"Drug: Betamethasone",{"label":15,"type":16,"description":17,"interventionNames":18},"Comparison","NO_INTERVENTION","Infants who do not meet criteria to receive treatment",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DRUG","Betamethasone","Infants who meet clinical criteria will receive a 5-day course of postnatal betamethasone: 0.125 mg\u002Fkg\u002Fdose IM every 24 hours for 3 days then 0.0625 mg\u002Fkg\u002Fdose IM every 24 hours for 2 days",[9],[26],{"name":27,"affiliation":28,"role":29},"Jordan Kase, MD","Maria Fareri Children's Hospital","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","914-493-8558","jordan.kase@wmchealth.org",{"name":36,"role":32,"phone":33,"phoneExt":18,"email":37},"Wendi Gu, MD","wendi.gu@wmchealth.org",[39],{"facility":40,"status":18,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Maria Fareri Children's Hospital at Westchester Medical Center","Valhalla","New York","10595","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-73.77513,41.07482,{"lat":50,"lon":49},[53],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Khang Nguyen","MD","100627369","phase-2-can-betamethasone-given-after-birth-help-extremely-premature-babies-come-off-breathing-support-safely-and-effectively-100627369",false,"NCT07447739","Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?","Efficacy and Safety of Postnatal Betamethasone for Respiratory Weaning in Extremely Low Gestational Age Neonates (ELGANs) in a Prospective Cohort - Proof of Concept Pilot Study","Inclusion Criteria:\n\n* Infants born at less than 28 weeks gestation age\n* Admitted to WMC NICU prior to day of life 35\n\nExclusion Criteria:\n\n* Infants with major congenital or chromosomal abnormalities.\n* Death prior to DOL 8.\n* Previous exposure to postnatal steroids","ALL","28 Weeks",{"count":68,"type":69},100,"ESTIMATED","INTERVENTIONAL",[72],"PHASE2","The goal of this study is to determine if giving a steroid medication (specifically, betamethasone) after birth can help extremely premature babies (born before 28 weeks) come off breathing machines safely and reduce their risk of chronic lung disease associated with prematurity. Only babies who meet treatment criteria will receive this medication. Babies who do not meet treatment criteria will not receive medication.\n\nThe main questions it aims to answer are:\n\n* Does betamethasone make it easier for babies to come off a breathing machine?\n* Does betamethasone cause any harmful side effects on growth or development?\n\nAll babies in this study will:\n\n* Receive standard NICU care, with or without betamethasone\n* Have their progress, growth, and development followed over time",[75,76],"Respiratory Distress Syndrome (RDS)","Bronchopulmonary Dysplasia (BPD)",[78,79,80,81,82],"respiratory distress syndrome","bronchopulmonary dysplasia","extremely low gestational age neonates","postnatal corticosteroids","betamethasone","NOT_YET_RECRUITING","2026-02-26",{"date":86,"type":87},"2026-03-03","ACTUAL",{"date":89,"type":69},"2026-04",{"date":91,"type":69},"2029-03",{"name":56,"class":6},1]