[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556043":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":12,"centralContacts":29,"locations":35,"responsibleParty":53,"collaborators":57,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":12,"studyType":75,"phases":76,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":38,"whyStopped":12,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Iowa","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","No medication administration. Standard of care medications will be offered.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Post Closure","ACTIVE_COMPARATOR","Once the fascia has been closed, the PLIA will be administered using a pediatric catheter.",[18],"Combination Product: Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)",{"label":20,"type":15,"description":21,"interventionNames":22},"Throughout Procedure","The injection will be performed throughout the surgical procedure.",[18],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":12},"COMBINATION_PRODUCT","Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)","Weight 50-74.9 kg:\n\n* ropivacaine 100mg\u002Fepinephrine 50 mcg\u002Fketorolac 15mg in NaCl 0.9% 60mL\n* 2 vials of this for 120mL total\n\nWeight 75-99.9 kg:\n\n* Ropivacaine 150mg\u002Fepinephrine 100 mcg\u002Fketorolac 15mg in NaCl 0.9% 60mL\n* 2 vials of this for 120mL total\n\nWeight 100+ kg:\n\n* Ropivacaine 200mg\u002Fepinephrine 150 mcg\u002Fketorolac 15 mg in NaCl 0.9% 60mL\n* 2 vials of this for 120mL total",[14,20],[30],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},"Ashley S Kochuyt","CONTACT","319-384-5101","ashley-kochuyt@uiowa.edu",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"University of Iowa Health Care","RECRUITING","Iowa City","Iowa","52242","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-91.53017,41.66113,{"lat":48,"lon":47},[51],{"name":52,"role":32,"phone":33,"phoneExt":12,"email":34},"Ashley Kochuyt",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"SPONSOR_INVESTIGATOR","Michael C Willey","Assistant Professor of Orthopedics and Rehabilitation",[58],{"name":59,"class":6},"Northwestern University","100556043","phase-2-can-plia-reduce-early-post-operative-pain-after-pao-surgery-100556043",false,"NCT06519955","Can PLIA Reduce Early Post-operative Pain After PAO Surgery?","Peri-incisional Local Infiltration to Improve Pain Control After Periacetabular Osteotomy","PILA PAO","Inclusion Criteria:\n\n* Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics.\n\nExclusion Criteria:\n\n* Unable to provide informed consent.\n* Pregnant or breast-feeding individuals\n* Prisoner or ward of the state\n* Allergy or medical contradiction to any of the study medications\n* Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded",true,"ALL","13 Years","50 Years",{"count":73,"type":74},120,"ESTIMATED","INTERVENTIONAL",[77,78],"PHASE2","PHASE3","The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are:\n\n1. Does PLIA impact post-operative pain after PAO?\n2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO?\n3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart.\n\nResearchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.",[81],"Hip Dysplasia",[81,83,84,85],"Periacetabular Osteotomy","PLIA","Peri-Incisional Local Infiltrative Anesthesia","2026-04-14",{"date":88,"type":89},"2026-04-17","ACTUAL",{"date":91,"type":89},"2024-10-03",{"date":93,"type":74},"2026-09",{"name":55,"class":6},1]