[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581617":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":47,"centralContacts":55,"locations":60,"responsibleParty":81,"collaborators":42,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":42,"eligibilityCriteria":89,"healthyVolunteers":85,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":42,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":108,"overallStatus":63,"whyStopped":42,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"RenJi Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CD70-targeted immunoPET imaging","EXPERIMENTAL","Enrolled patients will undergo a CD70-targeted immunoPET\u002FCT scanning.",[13,14,15,16,17],"Drug: [18F]F-RESCA-RCCB6","Drug: [18F]F-RESCA-R8B4","Drug: [68Ga]Ga-NOTA-R8B4","Drug: [18F]F-RESCA-RD06","Drug: [68Ga]Ga-NOTA-RD06",[19,26,32,38,43],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","[18F]F-RESCA-RCCB6","Enrolled patients will receive 0.01-0.1 mCi\u002Fkg of \\[18F\\]RCCB6. ImmunoPET\u002FCT imaging will be acquired 1-2 hours after \\[18F\\]RCCB6 injection.",[9],[25],"[18F]RCCB6",{"type":20,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"[18F]F-RESCA-R8B4","Enrolled patients will receive 0.01-0.1 mCi\u002Fkg of \\[18F\\]R8B4. ImmunoPET\u002FCT imaging will be acquired 1-2 hours after \\[18F\\]R8B4 injection.",[9],[31],"[18F]R8B4",{"type":20,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"[68Ga]Ga-NOTA-R8B4","Enrolled patients will receive 0.01-0.1 mCi\u002Fkg of \\[68Ga\\]R8B4. ImmunoPET\u002FCT imaging will be acquired 1-2 hours after \\[68Ga\\]R8B4 injection.",[9],[37],"[68Ga]R8B4",{"type":20,"name":39,"description":40,"armGroupLabels":41,"otherNames":42},"[18F]F-RESCA-RD06","Enrolled patients will receive 0.01-0.1 mCi\u002Fkg of \\[18F\\]F-RESCA-RD06. ImmunoPET\u002FCT imaging will be acquired 1-2 hours after \\[18F\\]F-RESCA-RD06 injection.",[9],null,{"type":20,"name":44,"description":45,"armGroupLabels":46,"otherNames":42},"[68Ga]Ga-NOTA-RD06","Enrolled patients will receive 0.01-0.1 mCi\u002Fkg of \\[68Ga\\]Ga-NOTA-RD06. ImmunoPET\u002FCT imaging will be acquired 1-2 hours after \\[68Ga\\]Ga-NOTA-RD06 injection.",[9],[48,52],{"name":49,"affiliation":50,"role":51},"Jianjun Liu, Ph.D. & M.D.","Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University","STUDY_CHAIR",{"name":53,"affiliation":50,"role":54},"Weijun Wei, Ph.D. & M.D.","PRINCIPAL_INVESTIGATOR",[56],{"name":53,"role":57,"phone":58,"phoneExt":42,"email":59},"CONTACT","15000083153","wwei@shsmu.edu.cn",[61],{"facility":62,"status":63,"city":64,"state":42,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Renji Hospital, School of Medicine, Shanghai Jiao Tong University","RECRUITING","Shanghai","200127","China","CN",{"type":69,"coordinates":70},"Point",[71,72],121.45806,31.22222,{"lat":72,"lon":71},[75,77],{"name":76,"role":57,"phone":58,"phoneExt":42,"email":59},"Weijun Wei",{"name":78,"role":57,"phone":79,"phoneExt":42,"email":80},"Shuxian An","17717453484","anshuxian@shsmu.edu.cn",{"type":82,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR","100581617","phase-2-cd70-targeted-immunopet-imaging-of-malignant-cancers-100581617",false,"NCT06852638","CD70-targeted immunoPET Imaging of Malignant Cancers","CD70-targeted PET\u002F CT in the Diagnosis of Malignant Cancers","Inclusion Criteria:\n\n* Aged 18-80 year-old and of either sex；\n* Histologically confirmed diagnosis of renal cancer (especially ccRCC)\u002Flymphoma\u002FNPC or suspected renal cancer\u002Flymphoma\u002FNPC by diagnostic imaging;\n* Capable of giving signed informed consent, including compliance with the requirements and restrictions in the informed consent form (ICF) and this protocol.\n\nExclusion Criteria:\n\n* Pregnancy；\n* Severe hepatic and renal insufficiency;\n* Allergic to single-domain antibody radiopharmaceuticals.","ALL","18 Years","80 Years",{"count":94,"type":95},300,"ESTIMATED","INTERVENTIONAL",[98],"PHASE2","This study aims to determine the value of cluster of differentiation (CD70)-targeted immuno-positron emission tomography\u002Fcomputed tomography (immunoPET\u002FCT) imaging for diagnosing human malignancies, including renal cell carcinoma (particularly clear cell renal cell carcinoma), lymphoma, and nasopharyngeal carcinoma (NPC), among others.",[101,102,103,104,105,106,107],"Renal Cancer","Renal Clear Cell Carcinoma","Lymphoma","Lymphoma, Large B-Cell, Diffuse","Follicular Lymphoma","Mantle Cell Lymphoma","Nasopharyngeal Carcinoma",[109,110,101,103,107],"The cluster of differentiation (CD70)","ImmunoPET","2026-05-07",{"date":113,"type":114},"2026-05-12","ACTUAL",{"date":116,"type":114},"2024-12-23",{"date":118,"type":95},"2026-12-23",{"name":5,"class":6},1]