[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554042":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":25,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":25,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":69,"whyStopped":25,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":25},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group (A)","ACTIVE_COMPARATOR","Fluoride releasing filled resin based pit and fissure sealant using UltraSeal XT™ plus by Ultradent",[13],"Other: UltraSeal XT™ plus by Ultradent",{"label":15,"type":16,"description":17,"interventionNames":18},"Interventional group (B)","EXPERIMENTAL","Bioactive pit and fissure sealant using BioCoat® by Premier®",[19],"Other: BioCoat® by Premier®",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BioCoat® by Premier®","BioCoat is a 56% filled resin formula that provides added strength and excellent long-term resistance to wear ؤomparable to flowable composites.",[15],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"UltraSeal XT™ plus by Ultradent","UltraSeal XT plus is a 58%-filled resin fluoride-releasing sealant. It is strong and has high wear resistant",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Samaa Salah, Msc","CONTACT","01009273452","samaa.salah@dentistry.cu.edu.eg",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Samaa Salah Eldin Abd Elfattah","Assistant lecturer in pediatric dentistry department, faculty of Dentistry","100554042","phase-2-clinical-efficiency-of-bioactive-pit-and-fissure-sealant-100554042",false,"NCT06493942","Clinical Efficiency of Bioactive Pit and Fissure Sealant","Clinical Evaluation of Bioactive Versus Filled Resin Based Pit & Fissure Sealants in First Permanent Molars: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Inclusion Criteria of participants:\n\n  * Patients with caries susceptible fiss- ures in fully erupted first permanent molars showing nosigns of caries.\n  * Co-operative patients approving to part- icipate in the trial.\n  * Good oral hygiene.\n* Inclusion Criteria of teeth:\n\n  * Caries susceptible occlusal pits and fissures.\n  * Intact contact with opposing teeth.\n  * Teeth with no previous restorations in other surfaces.\n\nExclusion Criteria:\n\n* Exclusion criteria of participants:\n\n  * patients with Disabilities, systemic disease or severe medical complications.\n  * patients have allergic history concerning methacrylate.\n  * patients with rampant caries, xerostomia, evidence of severe bruxism, clenching, or tempromandibular joint disorders\n  * participants who show lack of compliance.\n* Exclusion criteria of teeth:\n\n  * Carious pits and fissures.\n  * Developmental tooth defect.\n  * Partially erupted teeth\n  * Periapical pathology or signs of pulpal pathology.\n  * Tooth hypersensitivity.\n  * Heavy occlusion and occlusal contacts.",true,"ALL","6 Years","10 Years",{"count":52,"type":53},40,"ESTIMATED","INTERVENTIONAL",[56],"PHASE2","This study will compare the performance of newly introduced bioactive resin based pits and fissure sealant versus fluoride releasing filled resin based pits and fissure sealant in posterior molars prone to carious lesions of fissures in patients at risk of caries. Visual tactile examination and VistaCAM will be used for evaluation.",[59],"Pit and Fissure Sealant",[61,62,63,64,65,66,67,68],"dental sealant","pit and fissure sealant","fissure sealant","Bioactive dental sealant","Tooth sealant","Fissure sealants","Dental sealants","Pit sealants","NOT_YET_RECRUITING","2024-07-02",{"date":72,"type":73},"2024-07-10","ACTUAL",{"date":75,"type":53},"2024-08-01",{"date":77,"type":53},"2025-09-30",{"name":5,"class":6}]