[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100465092":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":25,"locations":31,"responsibleParty":49,"collaborators":24,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":24,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":24,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":24,"overallStatus":33,"whyStopped":24,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"C-READY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)","EXPERIMENTAL","Self-management and goal-setting cognitive remediation",[13],"Behavioral: CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)",{"label":15,"type":6,"description":16,"interventionNames":17},"Wait-List Control Group","Will receive the same C-READY intervention after a 4-week wait period",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)","Manualized cognitive remediation intervention that includes 1) skills-based remediation (metacognitive training), 2) parent training, and 3) cognitive behavioral approaches. Intervention targets self-management and goal-setting skill building to promote independence in activities necessary for transition of care.",[9,15],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Donna Murdaugh, PhD","CONTACT","2056382189","donnamurdaugh@uabmc.edu",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-86.80249,33.52066,{"lat":43,"lon":42},[46],{"name":47,"role":28,"phone":48,"phoneExt":24,"email":24},"Murdaugh","2056382135",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Donna Murdaugh","Assistant Professor","100465092","phase-2-cognitive-remediation-intervention-to-prepare-for-transition-of-care-100465092",false,"NCT05336201","Cognitive Remediation Intervention to Prepare for Transition of Care","The Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) Intervention: A Randomized Controlled Trial for Adolescents With Sickle Cell Disease to Prepare for Transition of Care","Inclusion Criteria:\n\n* Diagnosis of SCD (all genotypes)\n* Active follow-up at Children's of Alabama Hospital\n* Ages 10-18\n* English-speaking\n\nExclusion Criteria:\n\n* History of seizures or overt stroke\n* History of Intellectual Disability or Autism Spectrum Disorder\n* Inability to participate in the MRI scan, such as metal implants, neurostimulators, claustrophobia\n* Currently on psychotropic medications","ALL","10 Years","18 Years",{"count":64,"type":65},120,"ESTIMATED","INTERVENTIONAL",[68],"PHASE2","Randomized Controlled Trial (RTC) testing the efficacy of a telehealth adaptation of the Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) intervention to prepare adolescents with sickle cell disease for transition of care.",[71,72,73,74,75,76],"Sickle Cell Disease","Cognitive Impairment","Adolescent Behavior","Self Efficacy","Health-Related Behavior","Coping Skills","2026-02-25",{"date":79,"type":80},"2026-02-27","ACTUAL",{"date":82,"type":80},"2022-07-01",{"date":84,"type":65},"2027-06-30",{"name":5,"class":6},1]