[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100054059":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":43,"locations":53,"responsibleParty":157,"collaborators":159,"id":173,"slug":174,"hasResults":175,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":179,"eligibilityCriteria":180,"healthyVolunteers":181,"sex":182,"minAge":183,"maxAge":184,"enrollmentInfo":185,"targetDuration":25,"studyType":188,"phases":189,"briefSummary":191,"conditions":192,"keywords":197,"overallStatus":203,"whyStopped":25,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":213},{"fullName":5,"class":6},"Westat","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of Care and PrEP Choice at Enrollment","EXPERIMENTAL","Participants randomized to the intervention arm will be onboarded PrEP Choice at their Enrollment Visit.",[13],"Other: Standard of care and PrEP Choice at Enrollment",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care for the first 9 months followed by initiation of PrEP Choice at Month 9","ACTIVE_COMPARATOR","Participants randomized to the delayed arm will be onboarded to PrEP Choice at their Month 9 study visit.",[19],"Other: Standard of care followed by PrEP Choice at Month 9",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Standard of care and PrEP Choice at Enrollment","Standard of care includes a handout describing the different PrEP regimens as well as a handout describing DoxyPEP.\n\nPrEP Choice is a package of three mHealth tools:\n\n1. MyPrEP, a decision support website to help PrEP users choose their optimal PrEP method;\n2. PrEPsmart, a mobile app to support PrEP adherence for persons using on-demand PrEP (2-1-1 oral PrEP) by providing dosing reminders and feedback on levels of protection; and PrEPmate, a bidirectional short message service (SMS) texting platform with automated daily reminders for oral PrEP users and a triage function to help those experiencing difficulties.",[9],null,{"type":6,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"Standard of care followed by PrEP Choice at Month 9",[15],[30,34,36,40],{"name":31,"affiliation":32,"role":33},"Susan Buchbinder","San Francisco Department of Public Health","STUDY_CHAIR",{"name":35,"affiliation":32,"role":33},"Albert Liu",{"name":37,"affiliation":38,"role":39},"Lisa Hightow-Weidman, MD, MPH","Florida State University","PRINCIPAL_INVESTIGATOR",{"name":41,"affiliation":42,"role":39},"Sybil Hosek, PhD","University of Illinois at Chicago",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":25,"email":48},"Erin Healey","CONTACT","301-610-8703","ErinHealey@westat.com",{"name":50,"role":46,"phone":51,"phoneExt":25,"email":52},"Nancy Liu","718-980-3937","NancyLiu@westat.com",[54,72,89,106,123,140],{"facility":32,"status":25,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"San Francisco","California","94102","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-122.41942,37.77493,{"lat":64,"lon":63},[67,71],{"name":68,"role":46,"phone":69,"phoneExt":25,"email":70},"Emily Schaeffer","628-217-7456","emily.schaeffer@sfdph.org",{"name":35,"role":39,"phone":25,"phoneExt":25,"email":25},{"facility":73,"status":25,"city":74,"state":75,"zip":76,"country":58,"countryCode":59,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Children's National Medical Center","Washington D.C.","District of Columbia","20010",{"type":61,"coordinates":78},[79,80],-77.03637,38.89511,{"lat":80,"lon":79},[83,87],{"name":84,"role":46,"phone":85,"phoneExt":25,"email":86},"Justin Unternaher","202-476-1030","junternahe@childrensnational.org",{"name":88,"role":39,"phone":25,"phoneExt":25,"email":25},"Natella Rakhmanina",{"facility":90,"status":25,"city":91,"state":92,"zip":93,"country":58,"countryCode":59,"cosmosGeoPoint":94,"geoPoint":98,"contacts":99},"University of South Florida","Tampa","Florida","33612",{"type":61,"coordinates":95},[96,97],-82.45843,27.94752,{"lat":97,"lon":96},[100,104],{"name":101,"role":46,"phone":102,"phoneExt":25,"email":103},"Elizabeth Enriquez-Bruce","813-250-2574","enriquezbruce@usf.edu",{"name":105,"role":39,"phone":25,"phoneExt":25,"email":25},"Patricia Emmanuel",{"facility":107,"status":25,"city":108,"state":109,"zip":110,"country":58,"countryCode":59,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"University Illinois Chicago","Chicago","Illinois","60612",{"type":61,"coordinates":112},[113,114],-87.65005,41.85003,{"lat":114,"lon":113},[117,121],{"name":118,"role":46,"phone":119,"phoneExt":25,"email":120},"Rachel Jackson","312-996-6018","rjacks34@uic.edu",{"name":122,"role":39,"phone":25,"phoneExt":25,"email":25},"Kelly Bojan",{"facility":124,"status":25,"city":125,"state":126,"zip":127,"country":58,"countryCode":59,"cosmosGeoPoint":128,"geoPoint":132,"contacts":133},"Tulane University","New Orleans","Louisiana","70112",{"type":61,"coordinates":129},[130,131],-90.07507,29.95465,{"lat":131,"lon":130},[134,138],{"name":135,"role":46,"phone":136,"phoneExt":25,"email":137},"Leslie Kozina","504-988-5348","lkozina@tulane.edu",{"name":139,"role":39,"phone":25,"phoneExt":25,"email":25},"Tina Simpson",{"facility":141,"status":25,"city":142,"state":143,"zip":144,"country":58,"countryCode":59,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"St. Jude Children's Research Hospital","Memphis","Tennessee","38015",{"type":61,"coordinates":146},[147,148],-90.04898,35.14953,{"lat":148,"lon":147},[151,155],{"name":152,"role":46,"phone":153,"phoneExt":25,"email":154},"Mary Dillard","901-595-4083","Mary.dillard@stjude.org",{"name":156,"role":39,"phone":25,"phoneExt":25,"email":25},"Aditya Gaur",{"type":158,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[160,163,165,167,169,170],{"name":161,"class":162},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH",{"name":164,"class":162},"National Institute on Drug Abuse (NIDA)",{"name":166,"class":162},"National Institute of Mental Health (NIMH)",{"name":168,"class":162},"National Institutes of Health (NIH)",{"name":38,"class":6},{"name":171,"class":172},"The Emmes Company, LLC","INDUSTRY","100054059","phase-2-combatting-hiv-or-other-stis-early-choose-100054059",false,"NCT07510048","Combatting HIV Or Other STIs Early (CHOOSE)","Combatting HIV Or Other STIs Early (CHOOSE): An Integrated Strategy of Pre-Exposure Prophylaxis (PrEP) Mobile Health (mHealth) Support and Doxycycline Post-Exposure Prophylaxis (DoxyPEP)","CHOOSE","Inclusion Criteria\n\n* Age 13-24 years, inclusive;\n* Self-reports being at increased likelihood for HIV acquisition, defined as having anal sex with a male in their lifetime;\n* Owns an iOS or Android Smartphone and able to access all elements of the PrEP Choice package;\n* Not currently on PrEP and interested in learning more about PrEP;\n* Is not living with HIV;\n* Weighs at least 35 kg;\n* Willing to receive PrEP care from a provider at a participating ATN SC;\n* Able to understand, read, and speak English;\n* Able to participate at the study site; and\n* Willing and able to provide written informed consent.\n* If of legal age or otherwise able to provide independent informed consent as determined by local law and consistent with IRB policies: Willing and able to provide written informed consent for study participation.\n* If not of legal age or otherwise not able to provide independent informed consent as determined by local law and consistent with IRB policies: Parent or legal guardian is willing and able to provide written informed consent for study participation and potential participant is willing and able to provide written assent for study participation.\n\nExclusion Criteria:\n\n* Female;\n* In a mutually monogamous sexual relationship with a partner not living with HIV for the past 12 months;\n* Currently participating in an interventional trial of PrEP agents, or prior enrollment in HPTN 083, HPTN 083-01, or any other study of long-acting PrEP (including PURPOSE- 2 lenacapavir study);\n* Plan to move within 18 months to an area inaccessible to a participating ATN SC;\n* An employee of the participating SC; or\n* Any concurrent participation in other clinical trials or behavioral intervention studies without prior approval from the protocol team.\n* Any other medical, behavioral, or other conditions that in the opinion of the SC Project Lead could interfere with adherence to study procedures or the individual's ability to remain in the study for an 18-month period or compromise interpretation of study results.",true,"MALE","13 Years","24 Years",{"count":186,"type":187},200,"ESTIMATED","INTERVENTIONAL",[190],"PHASE2","The overarching goal of this project is to optimize the PrEP Choice integrated mHealth package and assess the efficacy and cost of PrEP Choice on PrEP initiation and adherence among young people. It is hypothesized that PrEP Choice will improve HIV PrEP uptake and adherence among young people and will be cost-effective to deliver to young people in the United States (U.S.). This study will also assess the uptake, adherence, and acceptability of DoxyPEP among young people.",[193,194,195,196],"HIV","STIs","STIs Prevention","HIV Prevention",[193,194,198,199,200,201,202],"sexually transmitted infection","PrEP","DoxyPEP","mobile health","mHealth","NOT_YET_RECRUITING","2026-07-10",{"date":206,"type":207},"2026-07-13","ACTUAL",{"date":209,"type":187},"2026-07-20",{"date":211,"type":187},"2029-03-30",{"name":5,"class":6},6]