[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600849":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":36,"centralContacts":40,"locations":50,"responsibleParty":66,"collaborators":65,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":65,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":53,"whyStopped":65,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Quaid-e-Azam Medical College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Zinc group","EXPERIMENTAL","Participants in this group will receive oral zinc following neonatal dosing guidelines.",[13],"Drug: Zinc sulfate",{"label":15,"type":10,"description":16,"interventionNames":17},"Probiotics group","Participants in this group will receive oral probiotics following neonatal dosing guidelines.",[18],"Drug: Probiotic lactobacillus rhamnosus GG",[20,28],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Zinc sulfate","Oral zinc sulfate syrup in a dose providing 5mg elemental zinc daily as adjuvant to phototherapy.",[9],[26,27],"ZnSO4","Zinc",{"type":21,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Probiotic lactobacillus rhamnosus GG","Oral Probiotic Lactobacillus rhamnosus GG drops daily as adjuvant to phototherapy.",[15],[33,34,35],"LGG","L. rhamnosus GG","Probiotic",[37],{"name":38,"affiliation":5,"role":39},"Malik M. Umair Fazal, MBBS, FCPS Paediatrics","PRINCIPAL_INVESTIGATOR",[41,46],{"name":38,"role":42,"phone":43,"phoneExt":44,"email":45},"CONTACT","+923318682681","+92622720235","umair.malik1622@gmail.com",{"name":47,"role":42,"phone":48,"phoneExt":44,"email":49},"Dr. Muhammad Anwar, MBBS, FCPS Neonatology","+923216820943","hmanwar157@yahoo.com",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Sadiq Abbasi Hospital, QAMC, Bahawalpur","RECRUITING","Bahawalpur","Punjab Province","63100","Pakistan","PK",{"type":60,"coordinates":61},"Point",[62,63],71.6752,29.39779,{"lat":63,"lon":62},null,{"type":39,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":65,"oldOrganization":65},"Malik Muhammad Umair Fazal","Dr. Malik Muhammad Umair Fazal","100600849","phase-2-comparison-of-zinc-and-probiotics-on-neonates-with-indirect-hyperbilirubinemia-undergoing-phototherapy-100600849",false,"NCT07102836","COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY","COMPARATIVE EFFECTS OF ZINC AND PROBIOTICS ON NEONATAL INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY","ZIPP","Inclusion Criteria:\n\n* 1\\. Term or Near term neonates 2. Age \\\u003C7 days at enrollment 3. Bilirubin levels within phototherapy range according to NICE bilirubin threshold charts 4. No identifiable pathology 5. Tolerating oral feeds 6. Parental or Guardian written informed consent taken.\n\nExclusion Criteria:\n\n* 1\\. Positive sepsis screen or clinical signs of infection 2. Direct hyperbilirubinemia 3. Gastrointestinal malformations 4. Oral intolerance 5. Requiring mechanical ventilation 6. Congenital anomalies 7. Parental or Guardian refusal to participate in study","ALL","0 Days","28 Days",{"count":81,"type":82},110,"ESTIMATED","INTERVENTIONAL",[85],"PHASE2","Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy. Aim is to compare efficacy of these two drugs in clearing bilirubin and reducing duration of phototherapy. Neonates will be randomly assigned to receive either drug alongside phototherapy.",[88,89],"Indirect Hyperbilirubinemia","Neonatal",[27,91,92,93,94,95,96,97,88],"Probiotics","Jaundice","Phototherapy","Neonates","Randomized Controlled Trial","Bilirubin","Enterohepatic Circulation","2025-07-30",{"date":100,"type":101},"2025-08-05","ACTUAL",{"date":103,"type":82},"2025-08-07",{"date":105,"type":82},"2026-05-07",{"name":5,"class":6},1]