[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546926":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":49,"responsibleParty":79,"collaborators":82,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":95,"sex":101,"minAge":102,"maxAge":47,"enrollmentInfo":103,"targetDuration":47,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":52,"whyStopped":47,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":130},{"fullName":5,"class":6},"Université du Québec à Trois-Rivières","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Saline Injection","EXPERIMENTAL","A single injection of saline solution",[13],"Drug: Saline Solution (NaCl 0,9%)",{"label":15,"type":16,"description":17,"interventionNames":18},"Corticosteroid Injection","ACTIVE_COMPARATOR","Usual care, consisting on a single injection of corticosteroids",[19],"Drug: Triamcinolone Acetonide",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Saline Solution (NaCl 0,9%)","Ultrasound\u002Ffluoroscopy-guided intra-articular injection of 0.25ml of 0.9% saline solution.",[9],[27],"Saline solution",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Triamcinolone Acetonide","Ultrasound-guided intra-articular injection 0.25ml (10 mg) of triamcinolone.",[15],[33],"Corticosteroid",[35],{"name":36,"affiliation":5,"role":37},"Tokiko Hamasaki, PhD","PRINCIPAL_INVESTIGATOR",[39,44],{"name":36,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","819-478-5011","2903","tokiko.hamasaki@uqtr.ca",{"name":45,"role":40,"phone":46,"phoneExt":47,"email":48},"Carlos Gevers-Montoro, PhD","819-979-0448",null,"carlos.geversmontoro@mcgill.ca",[50,69],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Centre Hospitalier de l'Université de Montréal - Physiatry","RECRUITING","Montreal","Quebec","H2W 1T6","Canada","CA",{"type":59,"coordinates":60},"Point",[61,62],-73.58781,45.50884,{"lat":62,"lon":61},[65],{"name":66,"role":40,"phone":67,"phoneExt":47,"email":68},"Dr Luong","514-890-8000","dien-hung.luong.med@ssss.gouv.qc.ca",{"facility":70,"status":52,"city":53,"state":54,"zip":71,"country":56,"countryCode":57,"cosmosGeoPoint":72,"geoPoint":74,"contacts":75},"Centre Hospitalier de l'Université de Montréal - Chirurgie plastique","H2X 0C1",{"type":59,"coordinates":73},[61,62],{"lat":62,"lon":61},[76],{"name":77,"role":40,"phone":67,"phoneExt":47,"email":78},"Dr Harris","patrick.harris.med@ssss.gouv.qc.ca",{"type":37,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"Tokiko Hamasaki","Assistant Professor",[83,85,87,89,91],{"name":84,"class":6},"Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal",{"name":86,"class":6},"McGill University",{"name":88,"class":6},"Université de Montréal",{"name":90,"class":6},"Centre hospitalier de l'Université de Montréal (CHUM)",{"name":92,"class":6},"Centre de Recherche du Centre Hospitalier de l'Université de Montréal","100546926","phase-2-corticosteroid-against-saline-injections-for-thumb-osteoarthritis-casitoa-100546926",false,"NCT06401317","Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)","Comparison of the Efficacy of Intra-Articular Corticosteroid Injections Versus Saline Solution for Thumb Osteoarthritis: Double-Blind Pragmatic Randomized Pilot Study","CASITOA","Inclusion Criteria:\n\n* aged ≥18 years;\n* diagnosis of TMO was confirmed by X-ray interpreted by a radiologist;\n* suffering from pain at the base of the thumb;\n* the attending physician deems that an intra-articular corticosteroid injection would be beneficial, rather than opting for other types of intervention such as surgery\n* can read, understand and answer in either French or English.\n\nExclusion Criteria:\n\n* having received one or more corticosteroid injections in the last 12 months or surgery on the affected thumb;\n* suffering from painful thumb caused by a trauma (e.g., fracture, sprain), rheumatoid arthritis, or De Quervain's tendonitis; and\n* being pregnant or breastfeeding; and\n* known allergies to any components of the solutions (triamcinolone acetonide, benzyl alcohol, carboxymethylcellulose sodium, hydrochloric acid, polysorbate, sodium chloride, or sodium hydroxide) or to iodinated contrast media.","ALL","18 Years",{"count":104,"type":105},40,"ESTIMATED","INTERVENTIONAL",[108],"PHASE2","Thumb osteoarthritis or trapeziometacarpal osteoarthritis (TMO) is a common and painful form of hand arthritis that limits thumb mobility and hand function, affecting patients' quality of life. Although corticosteroids injections are a typical treatment, their effectiveness has been challenged, and side effects have been reported. Recent studies suggest that saline injections, usually considered inactive, might be a viable treatment option. The primary goal of this study is to compare the effectiveness of saline injections versus corticosteroids injections in reducing TMO-related pain and improving hand function. In this study, 40 people with TMO will be randomly assigned to receive either a corticosteroids or a saline injection, without them or the doctors performing the injection knowing which one was administered (double blind). If saline injections prove more effective, they could provide a less harmful and cheaper therapeutic alternative for TMO patients.",[111],"Trapeziometacarpal Osteoarthritis",[113,114,115,116,117,118,119,120],"Corticosteroids","Feasibility","Blinding","Randomized controlled trial","Saline","Trapeziometacarpal osteoarthritis","Intra-articular injection","Pragmatic trial","2026-01-20",{"date":123,"type":124},"2026-01-22","ACTUAL",{"date":126,"type":124},"2025-11-04",{"date":128,"type":105},"2028-12-31",{"name":5,"class":6},2]