[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528795":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":34,"responsibleParty":54,"collaborators":57,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":11,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":11,"enrollmentInfo":69,"targetDuration":11,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":11,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Stony Brook University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"SBRT to the spine","EXPERIMENTAL",null,[13],"Radiation: SBRT to the spine",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":11},"RADIATION","Stereotactic body radiation therapy (SBRT) administered to spine metastases",[9],[20],{"name":21,"affiliation":22,"role":23},"Kartik Mani, MD PhD","Stony Brook Cancer Center","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":11,"email":29},"Hermina Munoz, RN","CONTACT","631-216-2990","hermina.munoz@stonybrookmedicine.edu",{"name":31,"role":27,"phone":32,"phoneExt":11,"email":33},"Lucia Joya","631-216-2998","lucia.joya@stonybrookmedicine.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Stony Brook University Hospital","RECRUITING","Stony Brook","New York","11794","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-73.14094,40.92565,{"lat":47,"lon":46},[50],{"name":51,"role":27,"phone":52,"phoneExt":11,"email":53},"Caterina Vacchi-Suzzi, PhD","631-216-2993","caterina.vacchi-suzzi@stonybrookmedicine.edu",{"type":23,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Kartik Mani","Assistant Professor of Medicine",[58],{"name":59,"class":6},"The University of Texas Health Science Center at San Antonio","100528795","phase-2-definitive-radiation-for-high-risk-spine-metastases-100528795",false,"NCT06165419","Definitive Radiation for High-Risk Spine Metastases","A Phase II Study Evaluating Definitive Radiosurgical Decompression in Patients With High-Risk Spinal Metastases","Eligible patients must have:\n\n* Any pathologically proven solid tumor diagnosis not of central nervous system origin with radiographic or pathologic evidence of metastatic disease\n* Metastatic spine involvement documented by imaging\n* Involvement of maximum 3 contiguous vertebral bodies at the index site\n* Intact neurologic function, or only minor neurologic deficits with muscle strength greater or equal to 4 out of 5 with or without steroids\n* An evaluation by an radiation oncology and orthopedic spine\u002Fneurosurgery attending\n* ECOG Performance Status of 0-3\n\nPatients are ineligible if they have:\n\n* An unstable spine defined as a Spinal Instability Neoplastic Score (SINS) greater than 12\n* Had previous surgery or radiation to address the target spinal metastases\n* Radiosensitive tumors (e.g. small cell lung cancer, lymphoma, multiple myeloma, and germ-cell tumors)","ALL","18 Years",{"count":70,"type":71},26,"ESTIMATED","INTERVENTIONAL",[74],"PHASE2","This study is looking at whether patients with cancer that has aggressively spread to the spine can be treated with stereotactic body radiation therapy only and avoid a large spine surgery",[77,78,79,80,81,82,83,84],"Metastatic Cancer","Metastatic Lung Cancer","Metastatic Breast Cancer","Metastatic Tumor","Metastatic Tumor of Bone","Metastatic Tumor to the Spine","Spine Metastases","Metastasis","2025-05-09",{"date":87,"type":88},"2025-05-14","ACTUAL",{"date":90,"type":88},"2023-12-14",{"date":92,"type":71},"2026-05-31",{"name":5,"class":6},1]