[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100109911":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":48,"collaborators":51,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":19,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":19,"enrollmentInfo":65,"targetDuration":19,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"1","OSA Patients considering surgical treatment",[12],"Drug: Propofol sedation",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DRUG","Propofol sedation","Patients receive an intravenous propofol infusion titrated to reach a target level of sedation, sleep with arousability to verbal stimuli.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Eric J Kezirian, MD, MPH","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","4242596559","ekezirian@mednet.ucla.edu",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"UCLA Santa Monica Medical Center","RECRUITING","Santa Monica","California","90401","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-118.49138,34.01949,{"lat":42,"lon":41},[45,47],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},"Eric Kezirian, MD, MPH",{"name":46,"role":23,"phone":19,"phoneExt":19,"email":19},{"type":23,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Eric J. Kezirian, MD, MPH","Professor, Head and Neck Surgery",[52,55],{"name":53,"class":54},"National Institutes of Health (NIH)","NIH",{"name":56,"class":6},"American Academy of Otolaryngology-Head and Neck Surgery Foundation","100109911","phase-2-drug-induced-sleep-endoscopy-for-upper-airway-evaluation-in-obstructive-sleep-apnea-100109911",false,"NCT00695214","Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea","Inclusion Criteria:\n\n* Adult patients with OSA considering surgical treatment\n\nExclusion Criteria:\n\n* Minors\n* Pregnant women\n* Patients unable to provide informed consent in English themselves\n* Prisoners\n* Allergy to propofol, soybean oil, egg lecithin or glycerol\n* Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)","ALL","18 Years",{"count":66,"type":67},800,"ESTIMATED","INTERVENTIONAL",[70],"PHASE2","Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.",[73],"Sleep Apnea, Obstructive",[75,76,77],"Obstructive Sleep Apnea","Propofol","Sleep Endoscopy","2026-06-29",{"date":80,"type":81},"2026-07-01","ACTUAL",{"date":83,"type":81},"2004-02",{"date":85,"type":67},"2035-06",{"name":5,"class":6},1]