[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100442880":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":28,"locations":37,"responsibleParty":57,"collaborators":27,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":27,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":27,"enrollmentInfo":71,"targetDuration":27,"studyType":74,"phases":75,"briefSummary":78,"conditions":79,"keywords":27,"overallStatus":40,"whyStopped":27,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Ascension Health","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early Adminstration of TXA + Intraoperative TXA","EXPERIMENTAL","This group receives 1 G of TXA as soon as possible after a diagnosis of an acute hip fracture if the patient meets inclusion and exclusion criteria. The group will also receive 2 grams of TXA total intraoperatively.",[13],"Drug: Tranexamic acid",{"label":15,"type":16,"description":17,"interventionNames":18},"Intraoperative only TXA","OTHER","This group will only receive the intraoperative TXA.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Tranexamic acid","TXA to be given at time of diagnosis in the emergency department (ED) in treatment group and at time of operation for both groups",[9,15],[26],"Lysteda",null,[29,34],{"name":30,"role":31,"phone":32,"phoneExt":27,"email":33},"Jacob Hinkley, DO, MS","CONTACT","810-606-5669","jacob.hinkley2@ascension.org",{"name":35,"role":31,"phone":32,"phoneExt":27,"email":36},"Jacob Lytle, DO","jacob.lytle@ascension.org",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Ascension Genesys Hospital","RECRUITING","Grand Blanc","Michigan","48439","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-83.62995,42.92753,{"lat":50,"lon":49},[53],{"name":54,"role":31,"phone":55,"phoneExt":27,"email":56},"Sandra Watt, MS, BSN","810-606-7713","sandra.watt@ascension.org",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Jacob Hinkley","Resident Physician","100442880","phase-2-effect-of-early-administration-of-txa-in-adult-hip-fractures-100442880",false,"NCT05047133","Effect of Early Administration of TXA in Adult Hip Fractures","Does Early Administration of Tranexamic Acid Decrease Perioperative Blood Loss in Addition to Intraoperative Tranexamic Acid for Hip Fracture Patients?","Inclusion Criteria:\n\n* 1\\. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation\n\nExclusion Criteria:\n\n1. Polytrauma patients\n2. Previous operation on the ipsilateral hip\n3. Patients with coagulopathies (Factor V Leiden, Sickle Cell Anemia, Etc.)\n4. Patients with \\\u003C 6-month history of thromboembolic event (DVT\u002FPE), Stroke, Cardiac Stents, or Myocardial Infarction (MI)\n5. History of seizure disorder\n6. Patients on birth control\n7. Pregnant Women\n8. Prisoners\n9. Active thromboembolic disease (DVT\u002FPE, MI, Stroke)",true,"ALL","18 Years",{"count":72,"type":73},170,"ESTIMATED","INTERVENTIONAL",[76,77],"PHASE2","PHASE3","This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical dosing pattern, and the dosing pattern employed at our institution, is 1 gram IV infused prior to incision followed by 1 gram IV infused at the time of wound closure.",[80],"Postoperative Blood Loss","2021-09-14",{"date":83,"type":84},"2021-09-16","ACTUAL",{"date":86,"type":84},"2021-09-01",{"date":88,"type":73},"2022-07-01",{"name":5,"class":6},1]