[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559621":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":36,"centralContacts":43,"locations":52,"responsibleParty":72,"collaborators":27,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":27,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":27,"studyType":89,"phases":90,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":55,"whyStopped":27,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Calcium Hydroxide","ACTIVE_COMPARATOR","Intracanal medication",[13],"Drug: Calcium Hydroxide Intracanal medication",{"label":15,"type":10,"description":11,"interventionNames":16},"Leddermix",[17],"Drug: Leddermix Intracanal medication",{"label":19,"type":10,"description":11,"interventionNames":20},"Asiaticoside",[21],"Drug: Asiaticoside Intracanal medication",[23,28,31],{"type":24,"name":25,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Calcium Hydroxide Intracanal medication",[9],null,{"type":24,"name":29,"description":29,"armGroupLabels":30,"otherNames":27},"Leddermix Intracanal medication",[15],{"type":24,"name":32,"description":32,"armGroupLabels":33,"otherNames":34},"Asiaticoside Intracanal medication",[19],[35],"centella asiatica",[37,41],{"name":38,"affiliation":39,"role":40},"Amany Bader, prof","Faculty of Dentistry Mansoura University","STUDY_DIRECTOR",{"name":42,"affiliation":39,"role":40},"Youssry Elhawary, prof",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":27,"email":48},"salem alqahtani, master","CONTACT","00201553553096","Salemamq@gmail.com",{"name":50,"role":46,"phone":51,"phoneExt":27,"email":48},"Ghada Abdelrazik","00201003455012",[53],{"facility":54,"status":55,"city":56,"state":27,"zip":27,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Mansoura university","RECRUITING","Al Mansurah","Egypt","EG",{"type":60,"coordinates":61},"Point",[62,63],31.38069,31.03637,{"lat":63,"lon":62},[66,68],{"name":45,"role":46,"phone":47,"phoneExt":27,"email":67},"salemamq@gmail.com",{"name":69,"role":46,"phone":70,"phoneExt":27,"email":71},"khalid aldhafeeri, master","00966532966229","van.gool17@hotmail.com",{"type":73,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Salem Abdulrahman Alqahtani","Principal investigator","100559621","phase-2-effectiveness-of-asiaticoside-as-intracanal-medication-on-infectiousinflammatory-contents-in-teeth-with-apical-periodontitis-100559621",false,"NCT06566508","Effectiveness of Asiaticoside as Intracanal Medication on Infectious\u002FInflammatory Contents in Teeth With Apical Periodontitis","Inclusion Criteria:\n\n• Single-rooted with pulp necrosis and apical periodontitis.\n\nExclusion Criteria:\n\nReceiving antibiotic treatment within the preceding 3 months.\n\n* Reporting systemic disease.\n* Teeth that could not be isolated with rubber dam.\n* Teeth with periodontal pockets deeper than 3 mm.",true,"ALL","20 Years","60 Years",{"count":87,"type":88},36,"ESTIMATED","INTERVENTIONAL",[91,92],"PHASE2","PHASE3","The objective of this study is to investigate \\"clinically\\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.",[95],"Intracanal Medication",[97,19,98],"Inflammation","Pulpal necrosis","2024-08-20",{"date":101,"type":102},"2024-08-22","ACTUAL",{"date":104,"type":102},"2023-11-20",{"date":106,"type":88},"2025-03-03",{"name":5,"class":6},1]