[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576473":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":58,"collaborators":35,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":35,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":35,"overallStatus":44,"whyStopped":35,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Armed Forces Institute of Dentistry, Pakistan","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"normal saline group","EXPERIMENTAL","In control group , canals will be irrigated with 5ml of normal saline at room temperature",[13],"Drug: Irrigation Solution",{"label":15,"type":10,"description":16,"interventionNames":17},"cryotherapy (cold saline group)","in cold saline group , canals will be irrigated with 5 ml of cold saline at a temperature of 2.5° C",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Irrigation Solution","normal saline will be used as irrigation solution",[15,9],[25],"normal saline irrigant",[27],{"name":28,"affiliation":29,"role":30},"Hira Amjad, BDS","Armed Forces Institude Of Dentistry","PRINCIPAL_INVESTIGATOR",[32,37],{"name":28,"role":33,"phone":34,"phoneExt":35,"email":36},"CONTACT","03345294071",null,"anmolamjad03@gmail.com",{"name":38,"role":33,"phone":39,"phoneExt":35,"email":40},"Kanza Zafar, BDS","03337808809","kanzazafar6@gmail.com",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Armed Forces Institute of Dentistry","RECRUITING","Rawalpindi","Punjab Province","46000","Pakistan","PK",{"type":51,"coordinates":52},"Point",[53,54],73.0479,33.59733,{"lat":54,"lon":53},[57],{"name":28,"role":33,"phone":34,"phoneExt":35,"email":36},{"type":30,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"Hira Amjad","Dr. Hira Amjad , Principal investigator and Resident Operative Dentistry and Endodontics","100576473","phase-2-effectiveness-of-cryotherapy-on-endodontic-pain-100576473",false,"NCT06785753","Effectiveness of Cryotherapy on Endodontic Pain","Effectiveness of Intracanal Cryotherapy on Post Operative Pain After Root Canal Therapy in Patients with Symptomatic Apical Periodontitis","Cy","Inclusion Criteria:\n\n* patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis\n* maxillary or mandibular single rooted teeth\n* systemically healthy patients\n* patients having pain score \\\u003C 8\n\nExclusion Criteria:\n\n* patients on preoperative analgesics or antibiotics within past 12 hours\n* teeth with calcified canals and previously treated teeth\n* tooth with immature apices or resorption\n* patients allergic to local anesthesia\n* pregnant or lactating mothers\n* patients who are immunocompromised .",true,"ALL","20 Years","40 Years",{"count":74,"type":75},60,"ESTIMATED","INTERVENTIONAL",[78],"PHASE2","This is a randomized , prospective , control trial to assess the effectiveness of intracanal cryotherapy on post operative pain after root canal treatment in patients with symptomatic apical periodontitis",[81],"Post Operative Pain","2025-01-19",{"date":84,"type":85},"2025-01-21","ACTUAL",{"date":87,"type":85},"2024-11-07",{"date":89,"type":75},"2025-05-08",{"name":5,"class":6},1]