[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538301":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":18,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":18,"enrollmentInfo":63,"targetDuration":18,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":75,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Alberta","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise Group","EXPERIMENTAL","The exercise intervention will consist of 24 supervised, heavy lifting strength training exercise sessions over a 12 week period. The exercise frequency will be two times per week. Main exercises will consist of barbell back squat, bench press, and dead lift.",[13],"Other: Experimental",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care Group","NO_INTERVENTION","Participants randomized to the usual care group will be asked to continue will their typical daily routine during the 12 week study period, and not begin any new exercise program to increase their exercise levels from baseline. They will not receive any information or education regarding exercise. After the postintervention assessments, participants in the usual care group will be offered a 4-week introduction to heavy lifting strength training program and\u002For referred to a community-based exercise program",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Experimental","Three primary exercises will be included in the exercise sessions for participants randomized to this group: barbell back squat, bench press, and dead lift\n\nThe weight will be progressively increased overtime based on participants' perceived exertion and repetitions in reserve. Number of repetitions performed for each exercise will begin at 10 repetitions in weeks 1-2, with gradual progression to lifting heavier loads of 3-5 sets of 1-5 repetitions between weeks 6-12.",[9],[9],[26],{"name":27,"affiliation":5,"role":28},"Kerry Courneya","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Stephanie Ntoukas","CONTACT","7804922829","ntoukas@ualberta.ca",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":18,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Edmonton","Alberta","Canada","CA",{"type":43,"coordinates":44},"Point",[45,46],-113.46871,53.55014,{"lat":46,"lon":45},[49,50],{"name":31,"role":32,"phone":18,"phoneExt":18,"email":34},{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"type":52,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100538301","phase-2-heavy-strength-training-in-head-and-neck-cancer-survivors-100538301",false,"NCT06289049","Heavy Strength Training in Head and Neck Cancer Survivors","Feasibility and Preliminary Efficacy of Heavy Lifting Strength Training Versus Usual Care in Head and Neck Cancer Survivors: A Randomized Controlled Trial","LIFTING2","Inclusion Criteria:\n\n* males and females, 18 years of age and older\n* any head and neck cancer subtype, stage, and treatment type\n* at least 1-year posttreatment with adequate shoulder range of motion (must meet minimum cutpoints for active flexion and abduction to be eligible)\n* no unmanaged medical conditions, alcohol, or drug abuse\n* approved for exercise by oncologist and a certified exercise physiologist or kinesiologist\n* ability to understand and communicate in English\n\nExclusion Criteria:\n\n* has met the Canadian Physical Activity strength training guidelines within the past one-month: at least two days per week of muscle and bone strength training activities using major muscle groups\n* currently involved in a different exercise trial or clinical drug trial","ALL","18 Years",{"count":64,"type":65},60,"ESTIMATED","INTERVENTIONAL",[68],"PHASE2","Despite improvements in treatments, head and neck cancer survivors (HNCS) still endure acute and chronic side effects such as loss of muscular strength, limitations in physical functioning, fatigue, and swallowing difficulties that impact quality of life (QoL) and limit return to work. Light-to-moderate intensity strength training (LMST) has been shown to improve some side effects. Heavy lifting strength training (HLST) may further improve outcomes in some populations, however, only one small pilot study has focused on HNCS. The LIFTING 2 trial will be the first to examine the feasibility and effects of a HLST program versus no exercise in HNCS.",[71,72,73,74],"Head and Neck Neoplasms","Head and Neck Cancer","Head and Neck Squamous Cell Carcinoma","Head and Neck Carcinoma",[76,77,78,79],"Strength Training","Exercise","Quality of Life","Randomized Controlled Trial","2026-02-04",{"date":82,"type":83},"2026-02-09","ACTUAL",{"date":85,"type":83},"2025-02-17",{"date":87,"type":65},"2026-06",{"name":5,"class":6},1]