[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100471389":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":43,"centralContacts":51,"locations":61,"responsibleParty":79,"collaborators":56,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":56,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":56,"studyType":96,"phases":97,"briefSummary":100,"conditions":101,"keywords":56,"overallStatus":64,"whyStopped":56,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"State University of New York at Buffalo","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Inhaled Isopropyl Alcohol","EXPERIMENTAL","If the subject is assigned to receive the isopropyl alcohol pad group, an isopropyl alcohol pad (Covidien Webcol 2 ply prep pad, saturated with 70% isopropyl alcohol) will be given to the subject, or the legal guardian. The alcohol pad will be held 1-2 cm under the subject's nares, the subject will be instructed to take deep breaths, inhaling through the nose as frequently as needed during the Emergency Department (ED) stay.",[13],"Other: Inhaled Isopropyl Alcohol",{"label":15,"type":16,"description":17,"interventionNames":18},"Oral Ondansetron","ACTIVE_COMPARATOR","If the subject is assigned to receive ondansetron treatment, subject will be provided with 4 mg ondansetron oral disintegrating tablet (ODT) for treatment.",[19],"Drug: Oral Ondansetron",{"label":21,"type":22,"description":23,"interventionNames":24},"Inhaled Placebo","PLACEBO_COMPARATOR","If the subject is assigned to receive the inhaled placebo, a normal saline pad (Hygea sterile saline wipe) will be given to the subject or the legal guardian. The saline wipe will be held under the subject's nares, the subject will be instructed to take deep breaths, inhaling through the nose as frequently as needed.",[25],"Other: Inhaled Placebo",[27,32,38],{"type":6,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"Isopropyl alcohol pad (Covidien Webcol 2 ply prep pads, saturated with 70% isopropyl alcohol) held 1-2 cm under the subject's nares",[9],[31],"Webcol",{"type":33,"name":15,"description":34,"armGroupLabels":35,"otherNames":36},"DRUG","4 mg oral disintegrating ondansetron tablet once",[15],[37],"Zofran",{"type":6,"name":21,"description":39,"armGroupLabels":40,"otherNames":41},"Normal saline pad (Hygea sterile saline wipe) held 1-2 cm under the subject's nares",[21],[42],"Inhaled Normal Saline'",[44,48],{"name":45,"affiliation":46,"role":47},"Alana Koehler, MD","SUNY Buffalo","PRINCIPAL_INVESTIGATOR",{"name":49,"affiliation":46,"role":50},"Heather Territo, MD","STUDY_DIRECTOR",[52,58],{"name":53,"role":54,"phone":55,"phoneExt":56,"email":57},"Haiping Qiao, MBBS, MS","CONTACT","7163230055",null,"hqiao@upa.chob.edu",{"name":45,"role":54,"phone":59,"phoneExt":56,"email":60},"315576264","alanakoe@buffalo.edu",[62],{"facility":63,"status":64,"city":65,"state":66,"zip":67,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"Oishei Children's Hospital","RECRUITING","Buffalo","New York","14203","United States","US",{"type":71,"coordinates":72},"Point",[73,74],-78.87837,42.88645,{"lat":74,"lon":73},[77],{"name":78,"role":54,"phone":55,"phoneExt":56,"email":57},"Haiping Qiao",{"type":47,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":56,"oldOrganization":56},"Susana Ruano","Pediatric Emergency Medicine Fellow","100471389","phase-2-inhaled-isopropyl-alcohol-for-treatment-of-nausea-100471389",false,"NCT05418244","Inhaled Isopropyl Alcohol for Treatment of Nausea","Inhaled Isopropyl Alcohol for the Treatment of Nausea in a Pediatric Emergency Department: A Open Label, Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients with a chief complaint of nausea or vomiting\n* Ages 7-178 years, both sexes\n* Weight ≥ 15 kg\n* Baxter Animated Retching Faces (BARF) nausea severity score ≥ 4\u002F10\n\nExclusion Criteria:\n\n* 1\\. Require IV access\n* Inability to breathe in\u002Fout through the nose\n* Anosmia (self- or parental report)\n* Allergy to isopropyl alcohol or ondansetron\n* Current or history of alcohol abuse\n* Inability to communicate feeling nauseous\n* Inability to follow directions regarding taking deep breaths through the nose\n* Known prolonged QT interval\n* Pregnancy\n* Received antiemetics within the last 8 hours\n* Currently taking apomorphine",true,"ALL","7 Years","17 Years",{"count":94,"type":95},84,"ESTIMATED","INTERVENTIONAL",[98,99],"PHASE2","PHASE3","To determine the efficacy of inhaled isopropyl alcohol in treating nausea\u002Fvomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.",[102,103,104],"Vomiting","Nausea","Children, Only","2025-10-03",{"date":107,"type":108},"2025-10-08","ACTUAL",{"date":110,"type":108},"2022-04-20",{"date":112,"type":95},"2026-06-30",{"name":5,"class":6},1]