[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595136":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":44,"responsibleParty":64,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":32,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":32,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":32,"overallStatus":47,"whyStopped":32,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"RDC Clinical Pty Ltd","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Levagen+","EXPERIMENTAL","Take 1 capsule twice daily with water after food. Each capsule will contain:\n\nA175mg containing 150 mg of palmitoylethanolamide (PEA). Total daily dose of 350mg Levagen+ containing 300 mg PEA.",[13],"Dietary Supplement: Levagen+",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Take 1 capsule twice daily with water after food. Each capsule will contain microcrystalline cellulose \\[MCC\\].",[19],"Other: Placebo",[21,28],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Participants will take 1 capsule twice daily with water after food. Each capsule will contain: A175mg containing 150 mg of palmitoylethanolamide (PEA). Total daily dose of 350mg Levagen+ containing 300 mg PEA",[9],[26,27],"palmitoylethanolamide","PEA",{"type":29,"name":15,"description":30,"armGroupLabels":31,"otherNames":32},"OTHER","Participants will take 1 capsule twice daily with water after food. Each capsule will contain microcrystalline cellulose \\[MCC\\]",[15],null,[34],{"name":35,"affiliation":36,"role":37},"Ramasamy Venkatesh","Gencor Pacific","STUDY_DIRECTOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":32,"email":43},"Amanda Rao","CONTACT","+61(0)731024486","research@rdcglobal.com.au",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RDC Clinical","RECRUITING","Fortitude Valley","Queensland","4006","Australia","AU",{"type":54,"coordinates":55},"Point",[56,57],153.03178,-27.45706,{"lat":57,"lon":56},[60,62],{"name":40,"role":41,"phone":61,"phoneExt":32,"email":43},"+61 (07) 3102 4486",{"name":40,"role":63,"phone":32,"phoneExt":32,"email":32},"PRINCIPAL_INVESTIGATOR",{"type":65,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[67],{"name":68,"class":6},"Gencor Pacific Limited, Hong Kong","100595136","phase-2-levagen-efficacy-study-on-diabetic-peripheral-neuropathy-100595136",false,"NCT07028528","Levagen+ Efficacy Study on Diabetic Peripheral Neuropathy","A Randomized Placebo Controlled Trial Assessing the Efficacy of Levagen+ for Treating Symptoms of Diabetic Peripheral Neuropathy","Inclusion Criteria:\n\n* Adults aged 18-75 years.\n* Using prescribed glucose-lowering medications, including oral medications (stable dose for 3 months or more) and\u002For insulin for diabetes (type 1 or 2).\n* Scoring12 or more on the Self-reported Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS).\n* Able to provide informed consent.\n* Agree not to change current diet and\u002For exercise frequency or intensity during entire enrolment period.\n* Agree to not participate in another clinical trial during the study period.\n* Able to attend an ACL collection centre.\n\nExclusion Criteria:\n\n* Peripheral neuropathy due to causes other than diabetes mellitus (e.g. nutritional deficiencies; hereditary sensory neuropathy; paraneoplastic diseases; advanced liver disease; kidney disease; hypothyroidism; prolonged phenytoin, warfarin or immunosuppressive drug use; active infection \\[HIV, Lyme disease, Epstein-Barr virus, Hepatitis C, Shingles, Leprosy\\]; autoimmune disease \\[Sjogren syndrome, Lupus, Rheumatoid arthritis, Guillain-Barre syndrome\\]; trauma \u002F injury; toxins \\[heavy metals, chemicals\\]; antibiotics; or inflammatory conditions \\[vasculitis\\]).\n* Serious illness e.g., paraneoplastic diseases, advanced liver disease, kidney disease, hypothyroidism, mood disorders such as depression, anxiety or bipolar disorder, neurological disorders such as MS, or heart conditions, or peripheral vascular disease\n* Unstable illness e.g., diabetes and thyroid gland dysfunction, hypercholesterolemia\n* Current malignancy (excluding Basal Cell Carcinoma) or chemotherapy or radiotherapy treatment for malignancy within the previous 2 years.\n* Currently taking Coumadin (Warfarin), Heparin, Dalteparin, Enoxaparin or other anticoagulation therapy including low dose aspirin\n* Herbal medicines for pain relief including, but not limited to, medicinal cannabis, willow bark (Salix alba), Boswellia (Boswellia serrata) or turmeric\u002Fcurcumin (Curcuma longa).\n* Active smokers, nicotine use or drug (prescription or illegal substances) abuse.\n* Chronic past and\u002For current alcohol use (\\>14 alcoholic drinks per week)\n* Females attempting to conceive, pregnant or lactating\n* Allergic, sensitive or intolerant to any of the ingredients in active or placebo formula.\n* Difficulty swallowing capsules.\n* Participants who are currently participating in any other clinical trial or who have participated in any other clinical trial during the past 1 month.\n* Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion.","ALL","18 Years","75 Years",{"count":80,"type":81},80,"ESTIMATED","INTERVENTIONAL",[84],"PHASE2","The goal of this clinical trial is to assess the efficacy of Levagen+ supplementation for the symptoms of diabetic peripheral neuropathy (DPN) in patients with DPN.\n\nParticipants will have remote visits and attend a local pathology centre for blood draws. They will take the study product for 12 weeks, from baseline to week 12 they will have remote visits every 3 weeks.",[87],"Diabetic Peripheral Neuropathy","2025-07-21",{"date":90,"type":91},"2025-07-23","ACTUAL",{"date":93,"type":91},"2025-07-01",{"date":95,"type":81},"2026-05",{"name":5,"class":6},1]