[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536072":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":58,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Virginia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active study product","ACTIVE_COMPARATOR","400 mg of Magnesium Oxide and 400 mg Riboflavin in capsule formation",[13],"Drug: magnesium and riboflavin supplement",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo study product","PLACEBO_COMPARATOR","Inert placebo in capsule formation",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","magnesium and riboflavin supplement","Five capsules considered one dose of the intervention (one 400 mg magnesium capsule and four 100 mg riboflavin capsules)",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Stephanie Hartman, MD","UVA Student Health and Wellness","PRINCIPAL_INVESTIGATOR",[32,36],{"name":28,"role":33,"phone":34,"phoneExt":25,"email":35},"CONTACT","434-924-5362","slm8nh@virginia.edu",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Karen Ahern, BSN MBA","4340924-1549","kaa7p@virginia.edu",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"University of Virginia Student Health and Wellness Center","RECRUITING","Charlottesville","Virginia","22903","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-78.47668,38.02931,{"lat":53,"lon":52},[56],{"name":37,"role":33,"phone":57,"phoneExt":25,"email":39},"434-924-1549",{"type":30,"investigatorFullName":28,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Associate Director of Primary Care UVA Student Health & Wellness","100536072","phase-2-magnesium-and-riboflavin-treatment-for-post-concussion-headache-100536072",false,"NCT06260072","Magnesium and Riboflavin Treatment for Post-Concussion Headache","Inclusion Criteria:\n\n* Seen at University of Virginia Student Health and Wellness Center or Emergency Department for Initial Visit for Concussion;\n* Less than 3 days have elapsed since their injury;\n* Able to swallow capsules\n\nExclusion Criteria:\n\n* Concussion complicated by cranial bleed, skull fracture, additional severe injury;\n* Kidney disfunction or failure;\n* Significant gastro-intestinal dysfunction;\n* Varsity Athlete;\n* Two or more previous concussions;\n* Women who are pregnant or breast feeding;\n* Taking tetracycline, fluoroquinolone, iron digoxin, chlorpromazine or penicillamine","ALL","18 Years","40 Years",{"count":70,"type":71},108,"ESTIMATED","INTERVENTIONAL",[74],"PHASE2","This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.",[77],"Concussion, Intermediate",[79],"Concussion; Headache","2025-03-24",{"date":82,"type":83},"2025-03-27","ACTUAL",{"date":85,"type":83},"2020-02-10",{"date":87,"type":71},"2025-12-31",{"name":5,"class":6},1]