[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100376433":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":42,"centralContacts":46,"locations":52,"responsibleParty":72,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":41,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":41,"enrollmentInfo":87,"targetDuration":41,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":41,"overallStatus":96,"whyStopped":41,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm I (isopropyl alcohol)","EXPERIMENTAL","Patients receive isopropyl alcohol via nasal inhalation.",[13,14],"Drug: Isopropyl Alcohol","Other: Questionnaire Administration",{"label":16,"type":17,"description":18,"interventionNames":19},"Arm II (placebo)","PLACEBO_COMPARATOR","Patients receive placebo via nasal inhalation.",[20,14],"Other: Placebo",[22,30,37],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Isopropyl Alcohol","Given via nasal inhalation",[9],[28,29],"Isopropanol","Isopropanolol",{"type":6,"name":31,"description":25,"armGroupLabels":32,"otherNames":33},"Placebo",[16],[34,35,36],"placebo therapy","PLCB","sham therapy",{"type":6,"name":38,"description":39,"armGroupLabels":40,"otherNames":41},"Questionnaire Administration","Ancillary studies",[9,16],null,[43],{"name":44,"affiliation":5,"role":45},"Yvonne J Heung","PRINCIPAL_INVESTIGATOR",[47],{"name":48,"role":49,"phone":50,"phoneExt":41,"email":51},"Michael J Tang, MD","CONTACT","(832) 468-8895","MJTang@mdanderson.org",[53],{"facility":54,"status":41,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"M D Anderson Cancer Center","Houston","Texas","77030","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-95.36327,29.76328,{"lat":64,"lon":63},[67,70],{"name":68,"role":49,"phone":69,"phoneExt":41,"email":41},"Michael J. Tang, MD","832-468-8895",{"name":71,"role":45,"phone":41,"phoneExt":41,"email":41},"Michael J. Tang",{"type":73,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[75],{"name":76,"class":77},"National Cancer Institute (NCI)","NIH","100376433","phase-2-nasal-inhalation-of-isopropyl-alcohol-for-the-treatment-of-nausea-in-patients-with-cancer-100376433",false,"NCT04181463","Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer","Inhalation Approaches to Nausea: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Rate current severity of acute\u002Fchronic nausea \\>= 4 on NRS (Numeric Rating Scale)\n* Diagnosis of cancer\n* Able to read\u002Fwrite in English\n* Referred to supportive care service as an inpatient or outpatient\n* Rate anxiety as =\\\u003C 4 on ESAS-FS (Edmonton Symptom Assessment Scale-Financial Distress and Spiritual Pain)\n* Participants must agree to inhale isopropyl alcohol\n\nExclusion Criteria:\n\n* Received anti-emetics in the last 30 minutes\n* Received medical procedures (e.g. blood draws) which required exposure of isopropyl alcohol in the last 30 minutes\n* Inability to inhale through nares (including recent upper respiratory infection)\n* Known allergy to isopropyl alcohol\n* Delirium (i.e., score \\>= 7 on the Memorial Delirium Assessment Scale \\[MDAS\\])\n* Have never been on anti-emetics during the course of the treatment here (anti-emetic naive)","ALL","18 Years",{"count":88,"type":89},112,"ESTIMATED","INTERVENTIONAL",[92],"PHASE2","The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.",[95],"Malignant Neoplasm","NOT_YET_RECRUITING","2026-05-26",{"date":99,"type":100},"2026-05-27","ACTUAL",{"date":102,"type":89},"2026-11-05",{"date":104,"type":89},"2028-12-30",{"name":5,"class":6},1]