[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641205":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":39,"locations":46,"responsibleParty":62,"collaborators":31,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":31,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":31,"studyType":79,"phases":80,"briefSummary":83,"conditions":84,"keywords":31,"overallStatus":89,"whyStopped":31,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Oral magnesium group","EXPERIMENTAL","cases will receive preoperative oral magnesium dose of 150 mg at two hours before surgery.",[13],"Drug: Magnesium glycinate",{"label":15,"type":10,"description":16,"interventionNames":17},"Intravenous magnesium group","cases will receive intraoperative IV magnesium sulfate dose of 30 mg\u002Fkg (diluted in saline to a total volume of 10 ml) over 10 minutes (1ml\u002Fmin) after induction of anesthesia and before the start of surgical procedure.",[18],"Drug: Magnesium sulfate injection",{"label":20,"type":21,"description":22,"interventionNames":23},"Control group","PLACEBO_COMPARATOR","cases will receive oral lemon juice (10 ml) at two hours before surgery and will receive intraoperative IV (10 ml) of saline 0.9% over 10 minutes (1ml\u002Fmin) after induction of anesthesia and before the start of surgical procedure.",[24],"Other: Oral juice and intravenous saline",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Magnesium glycinate","cases will receive preoperative oral magnesium dose of 150 mg (10 ml of Magnesium Glycinate Liquid Trace syrup) at two hours before surgery, and will receive intraoperative IV (10 ml) of saline 0.9% over 10 minutes (1ml\u002Fmin) after induction of anesthesia and before the start of surgical procedure.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Magnesium sulfate injection","cases will receive oral lemon juice (10 ml) at two hours before surgery, and will receive intraoperative IV magnesium sulfate dose of 30 mg\u002Fkg (diluted in saline to a total volume of 10 ml) over 10 minutes (1ml\u002Fmin) after induction of anesthesia and before the start of surgical procedure.",[15],{"type":6,"name":37,"description":22,"armGroupLabels":38,"otherNames":31},"Oral juice and intravenous saline",[20],[40],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Osama M Rehab, MD","CONTACT","+201095210806","002","osamarehab@med.tanta.edu.eg",[47],{"facility":48,"status":31,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Tanta University Hospitals","Tanta","Gharbia Governorate","31527","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],31.00192,30.78847,{"lat":58,"lon":57},[61],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Osama Rehab","lecturer of anesthesiology, surgical intensive care and pain medicine Tanta university","100641205","phase-2-oral-versus-intravenous-magnesium-on-emergence-delirium-100641205",false,"NCT07655817","Oral Versus Intravenous Magnesium on Emergence Delirium","Effect of Oral Versus Intravenous Magnesium on Emergence Delirium in Children Undergoing Adenotonsillectomy: A Two-Center, Randomized, Double-Blind, Placebo-Controlled Study","Inclusion Criteria:\n\n* Children aged 4 to 7 years\n* American Society of Anesthesiologist (ASA) Status I or II\n* Planned for an adenotonsillectomy procedure under sevoflurane general anesthesia.\n\nExclusion Criteria:\n\n* Parents declined to participate in the trial\n* Behavioral changes, neurological or psychiatric problems\n* Anticonvulsant or sedative drugs\n* Physical or developmental abnormalities\n* Allergies to magnesium\n* cardiovascular, renal, bone, or gastrointestinal diseases.","ALL","4 Years","7 Years",{"count":77,"type":78},360,"ESTIMATED","INTERVENTIONAL",[81,82],"PHASE2","PHASE3","This prospective randomized controlled study will be conducted to compare the effects of preoperative oral magnesium and intraoperative IV magnesium on the incidence and severity of emergence delirium in children undergoing adenotonsillectomy using sevoflurane anesthesia.",[85,86,87,88],"Magnesium","Emergence Delirium","Children","Adenotonsillectomy","NOT_YET_RECRUITING","2026-06-13",{"date":92,"type":93},"2026-06-18","ACTUAL",{"date":95,"type":78},"2026-06-24",{"date":97,"type":78},"2026-12-25",{"name":5,"class":6},1]