[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100515275":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":41,"locations":50,"responsibleParty":81,"collaborators":26,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":26,"eligibilityCriteria":90,"healthyVolunteers":86,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":26,"studyType":97,"phases":98,"briefSummary":101,"conditions":102,"keywords":26,"overallStatus":53,"whyStopped":26,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"Dow University of Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A","EXPERIMENTAL","Intra-operative wound irrigation of 0.9% solution saline solution",[13],"Procedure: 0.9% saline solution",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B","ACTIVE_COMPARATOR","No intra-operative wound lavage done",[19],"Procedure: Povidone-iodine Swab",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","0.9% saline solution","During emergency laparotomy, after the primary surgical procedure. the sheath will be sutured and the incision site will then be irrigated with three rounds of 1 liter of 0.9% saline solution, which will be completely aspirated before the closure of the incisional wound in experimental group.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Povidone-iodine Swab","No intra-operative wound lavage done, and wound would be cleaned with povidone doused swab.",[15],[32],"Control",[34,38],{"name":35,"affiliation":36,"role":37},"Omer Bin Khalid, Assist Prof.","Dr. Ruth F. M. Pfau Civil Hospital Karachi","PRINCIPAL_INVESTIGATOR",{"name":39,"affiliation":36,"role":40},"Imrana Zulfikar, Professor","STUDY_DIRECTOR",[42,46],{"name":35,"role":43,"phone":44,"phoneExt":26,"email":45},"CONTACT","+92 321 2040064","dromerkhalid@gmail.com",{"name":47,"role":43,"phone":48,"phoneExt":26,"email":49},"Afeera Ahmed, Undergraduate","+923352547330","afeeranws@gmail.com",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Dr. Ruth K. M. Pfau Civil Hospital Karachi","RECRUITING","Karachi","Sindh","74400","Pakistan","PK",{"type":60,"coordinates":61},"Point",[62,63],67.0104,24.8608,{"lat":63,"lon":62},[66,68,70,73,75,77,79],{"name":67,"role":43,"phone":44,"phoneExt":26,"email":45},"Omer Bin khalid, Asst. Prof",{"name":69,"role":37,"phone":26,"phoneExt":26,"email":26},"Omer Bin Khalid, FCPS-II",{"name":71,"role":72,"phone":26,"phoneExt":26,"email":26},"Afeera Bashir, Undergrad.","SUB_INVESTIGATOR",{"name":74,"role":72,"phone":26,"phoneExt":26,"email":26},"Azzam Ali, Undergrad.",{"name":76,"role":72,"phone":26,"phoneExt":26,"email":26},"Bushra Saeed Khan, FCPS-I",{"name":78,"role":72,"phone":26,"phoneExt":26,"email":26},"Rabbiyya Ali, FCPS-II",{"name":80,"role":72,"phone":26,"phoneExt":26,"email":26},"Imrana Zulfikar, FCPS-II",{"type":37,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Omer bin khalid","Principal Investigator (Assistant Professor)","100515275","phase-2-outcomes-of-high-volume-saline-irrigation-vs-povidone-iodine-solution-cleaning-of-iowi-in-preventing-ssis-in-emergency-laparotomies-100515275",false,"NCT05989386","Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies","Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of Intraoperative Incision Wound in Preventing Surgical Site Infections in Emergency Laparotomies: A Randomized Controlled Trial","Inclusion Criteria:\n\n* • Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi\n\n  * The age of patients should be between 18-60 years old.\n\nExclusion Criteria:\n\n* Diabetic patients\n* Immune-suppressed patients\n* Patients taking steroids\n* Patients undergoing chemo-radiotherapy.\n* Pregnant females\n* Previous abdominal surgery within the last 30 days.\n* Presence of concurrent abdominal wall infections.\n* Trauma Laparotomies\n* Large Bowel perforations","ALL","18 Years","60 Years",{"count":95,"type":96},200,"ESTIMATED","INTERVENTIONAL",[99,100],"PHASE2","PHASE3","The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are:\n\n* Incidence of SSI after intervention\n* Length of hospital stay\n\nParticipants will be randomly assigned to two groups receiving either of the two groups:\n\nGroup A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation.\n\nResearchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.",[103,104,105,106,107,108,109,110],"Surgical Site Infection","Surgical Wound","Surgical Incision","Emergency Laparotomies","Laparotomies","Post Operative Wound Infection","Wound Infection","Seroma","2025-06-14",{"date":113,"type":114},"2025-06-18","ACTUAL",{"date":116,"type":114},"2023-04-29",{"date":118,"type":96},"2025-12-29",{"name":5,"class":6},1]