[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586069":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":31,"responsibleParty":48,"collaborators":26,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":26,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":26,"maxAge":26,"enrollmentInfo":58,"targetDuration":26,"studyType":61,"phases":62,"briefSummary":65,"conditions":66,"keywords":26,"overallStatus":34,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"British University In Egypt","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"control","ACTIVE_COMPARATOR","15 patients were treated with Kenalog in orabase (Triamcinolone acetonide 0.1% oral paste 5g), four times (i.e., at 8 am, 12 noon, 4 pm, and 8 pm) a day for 7 days at intervention group.",[13],"Drug: topical application of Triamcinolone acetonide gel",{"label":15,"type":16,"description":17,"interventionNames":18},"Oxygenated gel Group","EXPERIMENTAL","15 patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on aphthous ulcers, which entails the application of 1-2 ml of oxygenated gel directly to the ulcer two times per day and this was repeated for 7 days",[19],"Drug: topical application of oxygenated gel",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","topical application of oxygenated gel","patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on aphthous ulcers, which entails the application of 1-2 ml of oxygenated gel directly to the ulcer two times per day and this was repeated for 7 days",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"topical application of Triamcinolone acetonide gel","patients were treated with Kenalog in orabase (Triamcinolone acetonide 0.1% oral paste 5g), four times (i.e., at 8 am, 12 noon, 4 pm, and 8 pm) a day for 7 days at intervention group.",[9],[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":26,"geoPoint":26,"contacts":40},"British University in Egypt","RECRUITING","Al Sherouk City","Cairo Governorate","11837","Egypt","EG",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":26,"email":45},"ahmed hamdy, phd","CONTACT","+201061112512","ahmed.esmaail@bue.edu.eg",{"name":47,"role":43,"phone":26,"phoneExt":26,"email":26},"Hamdy",{"type":49,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100586069","phase-2-oxygenated-gel-therapy-in-the-management-of-oral-aphthous-ulcers-100586069",false,"NCT06910579","Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers","Efficacy of Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Clinically diagnosed patients with chronic aphthous stomatitis measuring ≤6 mm in size in the oral cavity and who gave written consent for participation.\n* Only single ulcers were considered for the study.\n* Systemically healthy patients.\n\nExclusion Criteria:\n\n* The study excluded patients with a history of associated systemic disease.\n* Cases of chronic aphthous stomatitis (major), lesions of herpetic form, numerous aphthae, and smoking.\n* Patients with a history of hypersensitivity to the used agents.\n* Pregnancy and lactation","ALL",{"count":59,"type":60},30,"ESTIMATED","INTERVENTIONAL",[63,64],"PHASE2","PHASE3","Interventions of both groups:\n\nOxygenated gel Group: 15 patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on aphthous ulcers, which entails the application of 1-2 ml of oxygenated gel directly to the ulcer two times per day and this was repeated for 7 days.\n\nTriamcinolone acetonide Group: 15 patients were treated with Kenalog in orabase (Triamcinolone acetonide 0.1% oral paste 5g), four times (i.e., at 8 am, 12 noon, 4 pm, and 8 pm) a day for 7 days at intervention group.\n\nPatients in both groups were reexamined after treatment at different intervals (day 3, day 5, day 7, and day 10).",[67],"Aphthus Ulcer","2025-09-16",{"date":70,"type":71},"2025-09-18","ACTUAL",{"date":73,"type":71},"2025-03-15",{"date":75,"type":60},"2026-04-12",{"name":5,"class":6},1]