[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100414452":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":76,"collaborators":25,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":25,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":87,"maxAge":25,"enrollmentInfo":88,"targetDuration":25,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":25,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Stanford University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NSAIDS","EXPERIMENTAL","Following surgery will receive NSAID capsules following surgery. Will take online and phone surveys.",[13],"Drug: NSAID capsules",{"label":15,"type":10,"description":16,"interventionNames":17},"Opioids","Following surgery will receive opioid capsules following surgery. Will take online and phone surveys.",[18],"Drug: Opioid capsule",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","NSAID capsules","1, Ibuprofen 400-mg and 1, Acetaminophen 500-mg capsule per dosage",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Opioid capsule","1, Oxycodone 5-mg capsule and 1, placebo capsule per dosage",[15],[31],{"name":32,"affiliation":33,"role":34},"Amy Ladd, MD","Stanford Orthopaedic Surgery","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Deborah Kenney, MS OTR","CONTACT","6507217644","dkenney@stanford.edu",[42,60],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Stanford Health Care","RECRUITING","Redwood City","California","94063","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-122.23635,37.48522,{"lat":54,"lon":53},[57,59],{"name":37,"role":38,"phone":58,"phoneExt":25,"email":40},"(650) 721-7644",{"name":32,"role":34,"phone":25,"phoneExt":25,"email":25},{"facility":61,"status":44,"city":62,"state":63,"zip":64,"country":48,"countryCode":49,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"University of Utah Health Care","Salt Lake City","Utah","84112-",{"type":51,"coordinates":66},[67,68],-111.89105,40.76078,{"lat":68,"lon":67},[71,74],{"name":72,"role":38,"phone":25,"phoneExt":25,"email":73},"Mario Quesada, PS","u6051225@utah.edu",{"name":75,"role":34,"phone":25,"phoneExt":25,"email":25},"Angela Wang, MD",{"type":34,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Amy Ladd","Professor of Orthopaedic Surgery","100414452","phase-2-pain-relief-after-trapeziectomy-ibuprofen--acetaminophen-versus-oxycodone-100414452",false,"NCT04676802","Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone","Pain Relief After Trapeziectomy Without Opioids: Ibuprofen & Acetaminophen Versus Oxycodone","Inclusion Criteria:\n\n* Undergoing trapeziectomy for thumb osteoarthritis\n\nEnglish proficient,\n\nExclusion Criteria:\n\n* Pregnancy\n\nCurrent use of opioids\n\nConcurrent surgeries (ex. trapeziectomy combined with carpal tunnel release)\n\nInability to complete study forms (education, cognitive ability, mental status, medical status)\n\nAllergy or intolerance to Ibuprofen, Acetaminophen and\u002For Oxycodone\n\nLiver or kidney dysfunction, abnormal liver enzymes restricting use of acetaminophen or ibuprofen\n\nHistory of chronic heart failure, upper gastrointestinal bleeding or coagulopathy\n\nHistory of complex regional pain syndrome","ALL","45 Years",{"count":89,"type":90},121,"ESTIMATED","INTERVENTIONAL",[93],"PHASE2","In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.",[96,97],"Pain, Postoperative","Osteoarthritis Thumb","2026-06-08",{"date":100,"type":101},"2026-06-11","ACTUAL",{"date":103,"type":101},"2021-12-27",{"date":105,"type":90},"2027-08",{"name":5,"class":6},2]