[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100395454":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":59,"collaborators":30,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":30,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":30,"enrollmentInfo":72,"targetDuration":30,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":30,"overallStatus":81,"whyStopped":30,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Photodynamic Therapy","ACTIVE_COMPARATOR","One upper arm will be exposed to blue light therapy",[13],"Procedure: Photodynamic Therapy",{"label":15,"type":10,"description":16,"interventionNames":17},"Chemical Peels","One upper arm will be exposed to Jessner's Solution AND 35% Trichloroacetic acid peel",[18],"Drug: Chemical Peels",[20,26],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Photodynamic Therapy consists of (Levulan Kerastick (aminolevulinic acid HCL) topical solution, 20% + BLU-U Photodynamic Light Therapy)",[9],[25],"PDT",{"type":27,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","Chemical peels consists of a combination of Jessner's Solution: Composed of Salicylic Acid (14%), Medical Grade Lactic Acid (14%), Medical Grade Resorcinol (14%), Denatured Ethyl Alcohol AND 35% Trichloroacetic acid peels",[15],null,[32],{"name":33,"affiliation":5,"role":34},"Murad Alam, MD","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":30,"phoneExt":30,"email":39},"Alejandra Onate, M.S.","CONTACT","onate@northwestern.edu",[41],{"facility":42,"status":30,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Northwestern University Department of Dermatology","Chicago","Illinois","60611","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-87.65005,41.85003,{"lat":52,"lon":51},[55,58],{"name":33,"role":38,"phone":56,"phoneExt":30,"email":57},"312-695-6785","m-alam@northwestern.edu",{"name":33,"role":34,"phone":30,"phoneExt":30,"email":30},{"type":34,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Murad Alam","Professor of Dermatology","100395454","phase-2-pdt-vs-peels-for-treatment-of-actinic-keratoses-100395454",false,"NCT04429308","PDT vs Peels for Treatment of Actinic Keratoses","PDT Versus the Combination of Jessner's Solution and 35% TCA for Treatment of Actinic Keratoses on Upper Extremities: A Randomized Controlled Split-arm Trial","Inclusion Criteria:\n\n1. \\>18 years of age\n2. Interested in receiving treatment for actinic keratoses on the bilateral upper arms\n3. In good general health as assessed by the investigator\n4. Participants must have the ability to understand and the willingness to sign a written informed consent prior to registration on study\n\nExclusion Criteria:\n\n1. Patient pregnant or nursing\n2. Patient with extensive concurrent skin conditions (such as eczema, psoriasis, etc) on upper extremities that would interfere with treatment as determined by the treating physician\n3. Subject unwilling to sign an IRB approved consent form\n4. Participants who are unable to communicate or cooperate with the investigator due to language problems, poor mental development, or impaired cerebral function are not eligible",true,"ALL","18 Years",{"count":73,"type":74},60,"ESTIMATED","INTERVENTIONAL",[77],"PHASE2","The purpose of this study is to to compare photodynamic therapy (PDT) versus the combination of Jessner's solution and 35% trichloroacetic acid (TCA) chemical peels for the treatment of actinic keratoses on upper extremities.\n\nThis is a randomized clinical trial. Approximately 60 participants with actinic keratoses on both upper arms will be randomized to have one arm receive photodynamic therapy, while the contralateral arm receives Jessner's solution followed immediately by 35% TCA. AKs will be counted before treatment and 2-8 weeks after treatment. This study is a pilot study designed to determine the feasibility of this procedure.\n\nSubjects currently living in the Chicago metropolitan area and meet inclusion\u002Fexclusion criteria will be considered for enrollment.",[80],"Actinic Keratoses","NOT_YET_RECRUITING","2026-06-29",{"date":84,"type":85},"2026-07-01","ACTUAL",{"date":87,"type":74},"2026-08",{"date":89,"type":74},"2027-12",{"name":5,"class":6},1]