[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100415910":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":29,"responsibleParty":45,"collaborators":11,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":11,"enrollmentInfo":56,"targetDuration":11,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":11,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"University of Aarhus","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Neo-adjuvant pencil beam proton therapy: 55 Gy(RBE)\u002F44fx (1.25 Gy per fraction), two daily","EXPERIMENTAL",null,[13],"Radiation: Pencil beam proton radiotherapy",{"label":15,"type":10,"description":11,"interventionNames":16},"Definitive arm pencil beam proton therapy: 57.5-65Gy(RBE)\u002F46-52 fx (1.25 per fraction) two daily",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"RADIATION","Pencil beam proton radiotherapy","Doseescalated pencil beam proton Therapy",[15,9],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Camilla Kronborg, MD, PhD","CONTACT","+45 78450000","camkro@rm.dk",[30],{"facility":31,"status":32,"city":33,"state":11,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Danish Centre for Particle Therapy","RECRUITING","Aarhus","8200","Denmark","DK",{"type":38,"coordinates":39},"Point",[40,41],10.21076,56.15674,{"lat":41,"lon":40},[44],{"name":25,"role":26,"phone":11,"phoneExt":11,"email":11},{"type":46,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100415910","phase-2-pencil-beam-proton-therapy-for-pelvic-recurrences-in-rectal-cancer-patients-previously-treated-with-radiotherapy-100415910",false,"NCT04695782","Pencil Beam Proton Therapy for Pelvic Recurrences in Rectal Cancer Patients Previously Treated With Radiotherapy","ReRad II","Inclusion Criteria:\n\n* • Locally recurrent rectal cancer.\n\n  * Bioptically verified (adenocarcinoma )\n  * Available dose plan from primary radiotherapy\n  * Previous pelvic RT (\\>30Gy EQD2)\n  * Evaluated in MDT-conferences (Herlev, Aarhus)\n  * Age\\>18 years\n  * PS 0-2\n  * Adequate organ function\n  * Informed consent\n\nExclusion Criteria:\n\n* Non-resectable distant metastases (PET-CT)\n* Unable to undergo MRI, PET-CT\n* Inability to attend full course radiotherapy and follow up in the out patient clinic.","ALL","18 Years",{"count":57,"type":58},65,"ESTIMATED","INTERVENTIONAL",[61],"PHASE2","Study design:\n\nA prospective phase II, non-randomized observational study of dose-escalated pencil beam proton therapy re-irradiation for pelvic recurrences from rectal cancer.\n\nRe-irradiation is either a part of neo-adjuvant treatment or as a definitive treatment strategy for un-resectable recurrences.",[64],"Rectal Cancer Recurrent","2021-01-04",{"date":67,"type":68},"2021-01-05","ACTUAL",{"date":70,"type":68},"2020-10-10",{"date":72,"type":58},"2028-10-31",{"name":5,"class":6},1]