[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100521100":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":66,"collaborators":68,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":84,"maxAge":18,"enrollmentInfo":85,"targetDuration":18,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":47,"whyStopped":18,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Duke University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SeND Home Pathway","EXPERIMENTAL","Total parenteral nutrition (TPN) will begin within 72 hours of abdominal surgery. Calorie needs will be determined by indirect calorimetry. Nutritional shakes will begin when a liquid diet is started. These will be taken 3 times a day while in the hospital and for 4 weeks after discharge.",[13],"Dietary Supplement: Nutrition Supplement",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Nutrition","NO_INTERVENTION","Standard nutrition as determined by clinical providers.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Nutrition Supplement","Total parenteral nutrition (TPN) will be administered within 72 hours of abdominal surgery. Nutritional shakes will be started with a liquid diet and given 3 times a day. This will continue for 4 weeks after discharge.",[9],[26,27,28],"CLINIMIX E 8\u002F14 sulfite-free","CLINOLIPID 20%","Nutritional shakes",[30],{"name":31,"affiliation":32,"role":33},"Paul Wischmeyer, MD","Duke","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":18,"email":39},"Krista Haines, MD","CONTACT","919-681-3784","krista.haines@duke.edu",{"name":41,"role":37,"phone":42,"phoneExt":18,"email":43},"Hilary Winthrop","919-668-7238","hilary.winthrop@duke.edu",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Duke University Hospital","RECRUITING","Durham","North Carolina","27710","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-78.89862,35.99403,{"lat":57,"lon":56},[60,64],{"name":61,"role":37,"phone":62,"phoneExt":18,"email":63},"Shauna Howell","919-668-3771","shauna.eggertson@duke.edu",{"name":36,"role":65,"phone":18,"phoneExt":18,"email":18},"SUB_INVESTIGATOR",{"type":67,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[69,72],{"name":70,"class":71},"United States Department of Defense","FED",{"name":73,"class":74},"Baxter Healthcare Corporation","INDUSTRY","100521100","phase-2-personalized-nutrition-to-improve-recovery-in-trauma-100521100",false,"NCT06065202","Personalized Nutrition to Improve Recovery in Trauma","Personalized Targeted Nutrition Via StructurEd Nutrition Delivery Pathway to Improve Recovery of Physical Function in Trauma","SeND Home","Inclusion Criteria:\n\n* 15+ years old\n* Penetrating abdominal trauma requiring emergent major abdominal surgery\n* Admitted to the surgical ICU\n* Not expected to receive oral nutrition for 72 hours or more\n\nExclusion Criteria:\n\n* Patients who are unable to ambulate at baseline\n* Expected withdrawal of life-sustaining treatment within 48 hours\n* Prisoners\n* Positive pregnancy test for women of child bearing potential.","ALL","15 Years",{"count":86,"type":87},150,"ESTIMATED","INTERVENTIONAL",[90],"PHASE2","The purpose of this study is to determine if a particular method of providing nutrition improves the outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery following trauma and would require nutrition delivered via the bloodstream (called total parenteral nutrition or TPN). The nutrition method being tested is a structured nutrition delivery plan, called the SeND Home pathway, that involves TPN, oral nutrition supplements, and the use of a device (called an indirect calorimeter or IC) to measure calorie needs. Participants will be randomly assigned (like the flip of a coin) to the SeND Home program or standard of care nutrition. In the SeND Home program, participants will receive TPN, followed by oral nutrition supplements (shakes) for 4 weeks after discharge. The control group will follow standard of care nutrition delivery that begins during ICU stay and concludes at hospital discharge. Participants in both groups will undergo non-invasive tests that measure how much energy (calories) they are using, body composition, and muscle mass and complete walking and strength tests, and surveys about quality of life.",[93],"Abdominal Trauma",[95,96,97,98,99],"precision nutrition","critical care","trauma","parenteral nutrition","indirect calorimetry","2026-05-04",{"date":102,"type":103},"2026-05-06","ACTUAL",{"date":105,"type":103},"2024-04-12",{"date":107,"type":87},"2027-06-30",{"name":5,"class":6},1]