[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615219":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":11,"centralContacts":32,"locations":38,"responsibleParty":59,"collaborators":11,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":11,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":11,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":11,"overallStatus":41,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Guangdong Hengrui Pharmaceutical Co., Ltd","INDUSTRY",[8,14,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment group A","EXPERIMENTAL",null,[13],"Drug: SHR-2173 injection",{"label":15,"type":10,"description":11,"interventionNames":16},"Treatment group B",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"Treatment group C",[13],[21,26,29],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":11},"DRUG","SHR-2173 injection","SHR-2173 injection, with a total of 8 administrations",[9],{"type":22,"name":23,"description":27,"armGroupLabels":28,"otherNames":11},"SHR-2173 injection, with a total of 16 administrations",[15],{"type":22,"name":23,"description":30,"armGroupLabels":31,"otherNames":11},"SHR-2173 injection , with a total of 32 administrations",[18],[33],{"name":34,"role":35,"phone":36,"phoneExt":11,"email":37},"Zhe Zhang","CONTACT","+0518-81220121","zhe.zhang@hengrui.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"General hospital of eastern theater command","RECRUITING","Nanjing","Jiangsu","210002","China","CN",{"type":48,"coordinates":49},"Point",[50,51],118.77778,32.06167,{"lat":51,"lon":50},[54,57],{"name":55,"role":56,"phone":11,"phoneExt":11,"email":11},"Liangjing Lv","PRINCIPAL_INVESTIGATOR",{"name":58,"role":56,"phone":11,"phoneExt":11,"email":11},"Zhihong Liu",{"type":60,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100615219","phase-2-phase-ii-randomized-open-label-multicenter-clinical-study-evaluating-the-safety-efficacy-pharmacokinetics-and-pharmacodynamics-of-shr-2173-injection-in-patients-with-primary-membranous-nephropathy-100615219",false,"NCT07289763","Phase II Randomized, Open-label, Multicenter Clinical Study Evaluating the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of SHR-2173 Injection in Patients With Primary Membranous Nephropathy","Inclusion Criteria:\n\n1. Age 18-75 years, regardless of gender;\n2. Weight ≥40.0 kg at screening;\n3. Diagnosed as primary membranous nephropathy through kidney biopsy.\n\nExclusion Criteria:\n\n1. Secondary membranous nephropathy.\n2. Subjects developed rapidly progressive glomerulonephritis or required kidney transplantation.\n3. Subjects who have undergone kidney dialysis in the previous 12 months or are expected to require dialysis during the study period.\n4. Subjects who have a malignant tumor or a history of malignant tumor\n5. Subjects who have undergone major surgery within the previous 3 months, or plan to undergo major surgery during the study period.","ALL","18 Years","75 Years",{"count":71,"type":72},75,"ESTIMATED","INTERVENTIONAL",[75],"PHASE2","To investigate the safety, efficacy, pharmacokinetics, and pharmacodynamics of SHR-2173 injection in patients with primary membranous nephropathy",[78],"Primary Membranous Nephropathy","2026-01-22",{"date":81,"type":82},"2026-01-26","ACTUAL",{"date":84,"type":82},"2025-12-31",{"date":86,"type":72},"2027-09",{"name":5,"class":6},1]