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which POS has demonstrated activity (which can include candidiasis)\n* Panel B: has an investigator-assessed diagnosis of possible, probable, or proven IFI known or suspected to be cause by fungal pathogens against which POS has demonstrated activity (and cannot include candidiasis)\n* Has a central line (eg, central venous catheter, peripherally-inserted central catheter) in place or planned to be in place before beginning IV study intervention.\n* Has a body weight of ≥500 g\n* The participant (or legally acceptable representative) has provided documented informed consent for the study.\n\nExclusion Criteria\n\n* Has received POS within 30 days before Day 1\n* Has cystic fibrosis, pulmonary sarcoidosis, aspergilloma, or allergic bronchopulmonary aspergillosis\n* Has a known hereditary problem of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption\n* Has known or suspected active COVID-19 infection\n* Has a known hypersensitivity or other serious adverse reaction to any azole antifungal therapy, or to any other ingredient of the study intervention used\n* Has any known history of torsade de pointes, unstable cardiac arrhythmia or proarrhythmic conditions, a history of recent myocardial infarction, congenital or acquired QT interval (QT) prolongation, or cardiomyopathy in the context of cardiac failure within 90 days of first dose of study intervention\n* Has received any listed prohibited medications within the specified timeframes before the start of study intervention\n* Has a known hereditary problem of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption (Part B)\n* Has suspected\u002Fproven invasive candidiasis (Part B)\n* Has enrolled previously in the current study and been discontinued\n* Has QTc prolongation at screening \\>500 msec\n* Has significant liver dysfunction\n* Is hemodynamically unstable, exhibits hemodynamic compromise, or is not expected to survive at least 5 days","ALL","1 Day","2 Years",{"count":373,"type":374},40,"ESTIMATED","INTERVENTIONAL",[377],"PHASE2","This study aims to estimate the pharmacokinetics (PK) of posaconazole (POS, MK-5592) intravenous (IV) and powder for oral suspension (PFS) formulations in pediatric participants \\\u003C2 years of age with invasive fungal infection (IFI).",[380],"Invasive Fungal Infection","2025-09-17",{"date":383,"type":384},"2025-09-18","ACTUAL",{"date":386,"type":384},"2022-02-22",{"date":388,"type":374},"2026-12-31",{"name":5,"class":6},26]