[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512539":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":35,"centralContacts":36,"locations":46,"responsibleParty":65,"collaborators":35,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":35,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":35,"enrollmentInfo":77,"targetDuration":35,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":49,"whyStopped":35,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Mount Sinai Hospital, Canada","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Presacral Nerve Block","EXPERIMENTAL","Presacral nerve block using 20mL of local ropivacaine 5.0mg\u002Fml instilled in the presacral space",[13],"Drug: Ropivacaine injection",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Block","SHAM_COMPARATOR","20mL of normal saline (sham block) instilled in the presacral space",[19],"Drug: Normal saline injection",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Ropivacaine injection","Presacral nerve block using 20mL of local ropivacaine 5.0mg\u002Fml",[9],[27],"Naropin",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Normal saline injection","Sham block using 20 mL of normal saline (0.9% sodium chloride)",[15],[33,34],"Sham block","0.9% Sodium Chloride",null,[37,42],{"name":38,"role":39,"phone":40,"phoneExt":35,"email":41},"Mara Sobel, MD","CONTACT","416 586 8273","mara.sobel@sinaihealth.ca",{"name":43,"role":39,"phone":44,"phoneExt":35,"email":45},"Shakiba Ardestani, MD","6478185422","shakiba.ardestani@mail.utoronto.ca",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Mount Sinai Hospital","RECRUITING","Toronto","Ontario","M5G 1X5","Canada","CA",{"type":56,"coordinates":57},"Point",[58,59],-79.39864,43.70643,{"lat":59,"lon":58},[62],{"name":63,"role":39,"phone":40,"phoneExt":35,"email":64},"Mara Sobel, MD, MSc","Mara.Sobel@sinaihealth.ca",{"type":66,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100512539","phase-2-presacral-nerve-block-versus-sham-block-on-post-operative-pain-for-total-laparoscopic-hysterectomy-100512539",false,"NCT05953766","Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy","A Randomized Controlled Trial (RCT) Comparing Presacral Nerve Block Versus Sham Block on Post-operative Pain in Women Undergoing Total Laparoscopic Hysterectomy.","Inclusion Criteria:\n\n* 18 years of age or older\n* Undergoing total laparoscopic hysterectomy\n\nExclusion Criteria:\n\n* Previous presacral neurectomy\n* Concurrent surgical procedure other than salpingectomy and\u002For oophorectomy\n* Gynecological cancer beyond stage 1 disease\n* BMI \\> 50\n* Chronic opioid consumption\n* Fibromyalgia\n* Language barrier\n* Inability to communicate and provide consent",true,"FEMALE","18 Years",{"count":78,"type":79},60,"ESTIMATED","INTERVENTIONAL",[82],"PHASE2","The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg\u002Fml versus 20mL of normal saline (sham block) on post-operative pain following total laparoscopic hysterectomy.",[85],"Post-operative Pain",[87,88,89,90],"Hysterectomy","Presacral nerve block","Laparoscopy","Anesthesia","2026-03-31",{"date":93,"type":94},"2026-04-06","ACTUAL",{"date":96,"type":94},"2025-09-24",{"date":98,"type":79},"2026-07",{"name":5,"class":6},1]