[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497549":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":91,"collaborators":19,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":95,"sex":101,"minAge":102,"maxAge":19,"enrollmentInfo":103,"targetDuration":19,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":19,"overallStatus":34,"whyStopped":19,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Abramson Cancer Center at Penn Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Adjuvant Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT)","EXPERIMENTAL","The study intervention is Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) as part of the definitive treatment of gynecologic cancers in the post-hysterectomy, adjuvant setting. Patients will be treated with doses of 45 or 50.4 Gy in 1.8 Gy daily fractions. The volume treated will include the whole pelvis according to Radiation Therapy Oncology Group post-hysterectomy pelvis guidelines.",[13],"Radiation: Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT)",[15],{"type":16,"name":17,"description":11,"armGroupLabels":18,"otherNames":19},"RADIATION","Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT)",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Neil K Taunk, MD, MSCTS","University of Pennsylvania","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Project Manager","CONTACT","215-662-3790","RadOncCRU@PennMedicine.upenn.edu",[32,58,78],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Virtua Health","RECRUITING","Voorhees Township","New Jersey","08043","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-74.49062,40.4795,{"lat":44,"lon":43},[47,51,56],{"name":48,"role":28,"phone":49,"phoneExt":19,"email":50},"Kristina Montagno, RN, BSN","856-206-4728","kmontag1@virtua.org",{"name":52,"role":28,"phone":53,"phoneExt":54,"email":55},"Barbara Dillon, MSN, RN","856-247-7395","77395","bdillon@virtua.org",{"name":57,"role":24,"phone":19,"phoneExt":19,"email":19},"Graeme Williams, MD, MBA",{"facility":59,"status":34,"city":60,"state":61,"zip":62,"country":38,"countryCode":39,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Lancaster General Health - Ann B. Barshinger Cancer Institute","Lancaster","Pennsylvania","17601",{"type":41,"coordinates":64},[65,66],-76.30551,40.03788,{"lat":66,"lon":65},[69,73,76],{"name":70,"role":28,"phone":71,"phoneExt":19,"email":72},"Susan Tollett, BSN, RN, OCN","717-544-0511","susan.tollett@pennmedicine.upenn.edu",{"name":74,"role":28,"phone":71,"phoneExt":19,"email":75},"Alyson Eckert, BSN, RN, OCN","alyson.eckert@pennmedicine.upenn.edu",{"name":77,"role":24,"phone":19,"phoneExt":19,"email":19},"Pamela Boimel, MD, PhD",{"facility":23,"status":34,"city":79,"state":61,"zip":80,"country":38,"countryCode":39,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Philadelphia","19104",{"type":41,"coordinates":82},[83,84],-75.16362,39.95238,{"lat":84,"lon":83},[87,88,90],{"name":27,"role":28,"phone":19,"phoneExt":19,"email":30},{"name":89,"role":28,"phone":19,"phoneExt":19,"email":19},"MD",{"name":22,"role":24,"phone":19,"phoneExt":19,"email":19},{"type":92,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100497549","phase-2-proton-therapy-for-post-surgical-treatment-of-gynecologic-cancer-100497549",false,"NCT05758688","PROton Therapy for Post Surgical Treatment of GYNecologic Cancer","Adjuvant Proton Whole Pelvis Radiation Therapy for Treatment of Post-Surgical Gynecologic Cancers","PROPS GYN","Inclusion Criteria:\n\n* Histologically confirmed cervical or endometrial cancer\n* Indication for adjuvant whole pelvic radiation therapy, with or without systemic therapy\n* Age of 18 years or older\n* Written informed consent\n* ECOG of 0-2 within 3 months of enrolling\n\nExclusion Criteria:\n\n* Prior course of pelvic radiation\n* Metastatic disease outside of the pelvis\n* Active inflammatory bowel disease\n* Incapacity to provide informed consent","FEMALE","18 Years",{"count":104,"type":105},25,"ESTIMATED","INTERVENTIONAL",[108],"PHASE2","This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.",[111,112,113],"Cervical Cancer","Uterine Cancer","Endometrial Cancer","2026-06-09",{"date":116,"type":117},"2026-06-10","ACTUAL",{"date":119,"type":117},"2023-11-06",{"date":121,"type":105},"2026-12",{"name":5,"class":6},3]