[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100501340":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":30,"responsibleParty":46,"collaborators":11,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":11,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":11,"overallStatus":70,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Shanghai Proton and Heavy Ion Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"carbon ion therapy for unresectable local recurrent rectal cancer","EXPERIMENTAL",null,[13],"Radiation: Carbon ion radiation therapy DT: 74Gy\u002F20 fractions",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"RADIATION","Carbon ion radiation therapy DT: 74Gy\u002F20 fractions","patients with unresectable local recurrent rectal cancer will be treated with carbon ion radiation therapy as re-irradiation",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"Xin Cai, Doctor","CONTACT","+86 13901601072","xin.cai@sphic.org.cn",{"name":27,"role":23,"phone":28,"phoneExt":11,"email":29},"Zheng Wang, Doctor","+86 021-38296666","zheng.wang@sphic.org.cn",[31],{"facility":32,"status":11,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Shanghai Proton and Heavy ion center","Shanghai","Pudong","201321","China","CN",{"type":39,"coordinates":40},"Point",[41,42],121.45806,31.22222,{"lat":42,"lon":41},[45],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Xin Cai","Deputy chief physician","100501340","phase-2-re-irradiation-therapy-of-locally-recurrent-rectal-cancer-with-carbon-ion-100501340",false,"NCT05807984","Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion","A Prospective Phase II Clinical Study of Carbon Ion Re-irradiation in Unresectable Locally Recurrent Rectal Cancer","Inclusion Criteria:\n\n* 1\\) pathologically confirmed rectal adenocarcinoma (including mucinous adenocarcinoma and signet-ring cell carcinoma) and LRRC confirmed by biopsy or clinical diagnosis,\n* 2\\) received a radical operation for their primary tumor and regional lymph nodes,\n* 3\\) received chemo-radiation or radiation in pelvic before CIRT,\n* 4\\) received re-irradiation by CIRT after their pelvic radiotherapy.\n\nExclusion Criteria:\n\n* 1\\) received more than once prior radiotherapy in the same treatment field,\n* 2\\) time to the last radiotherapy was \\\u003C1 year,\n* 3\\) space between the lesion to organ at risk (OARs) (bladder or digestive tract) was too close (\\\u003C5 mm).","ALL","18 Years","80 Years",{"count":61,"type":62},31,"ESTIMATED","INTERVENTIONAL",[65],"PHASE2","Prospective phase II clinical study aim to explore the clinical outcome of patients with unresectable locally recurrent rectal cancer (LRRC) treated with re-irradiation by carbon ion radiotherapy (CIRT)",[68,69],"Rectal Cancer","Recurrent","NOT_YET_RECRUITING","2023-04-07",{"date":73,"type":74},"2023-04-11","ACTUAL",{"date":76,"type":62},"2023-05-01",{"date":78,"type":62},"2026-12-31",{"name":48,"class":6},1]