[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100437910":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":89,"collaborators":40,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":93,"sex":98,"minAge":99,"maxAge":40,"enrollmentInfo":100,"targetDuration":40,"studyType":103,"phases":104,"briefSummary":107,"conditions":108,"keywords":114,"overallStatus":45,"whyStopped":40,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Remote ischemic preconditioning","ACTIVE_COMPARATOR","3 cycles of blood pressure cuff inflations to occlusive pressure of 200 mmHg for 5 minutes and deflation for 5 minutes",[13],"Device: Remote ischemic preconditioning",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham remote ischemic preconditioning","SHAM_COMPARATOR","3 cycles of blood pressure cuff inflations to non-occlusive pressure of 60 mmHg for 5 minutes and deflation for 5 minutes (Control)",[19],"Device: Sham remote ischemic conditioning",[21,26],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"DEVICE",[9],[25],"RIPC",{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":29},"Sham remote ischemic conditioning",[15],[30],"Sham-RIPC",[32],{"name":33,"affiliation":34,"role":35},"Oladipupo Olafiranye, MD MS","VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX","PRINCIPAL_INVESTIGATOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","(214) 857-2923",null,"Oladipupo.Olafiranye@va.gov",[43,62,74],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA","RECRUITING","Pittsburgh","Pennsylvania","15240","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-79.99589,40.44062,{"lat":55,"lon":54},[58],{"name":59,"role":38,"phone":60,"phoneExt":40,"email":61},"Ning Feng","412-360-6191","ning.feng@va.gov",{"facility":34,"status":45,"city":63,"state":64,"zip":65,"country":49,"countryCode":50,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Dallas","Texas","75216-7167",{"type":52,"coordinates":67},[68,69],-96.80667,32.78306,{"lat":69,"lon":68},[72,73],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},{"name":33,"role":35,"phone":40,"phoneExt":40,"email":40},{"facility":75,"status":45,"city":76,"state":77,"zip":78,"country":49,"countryCode":50,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Hunter Holmes McGuire VA Medical Center, Richmond, VA","Richmond","Virginia","23249-0001",{"type":52,"coordinates":80},[81,82],-77.46026,37.55376,{"lat":82,"lon":81},[85],{"name":86,"role":38,"phone":87,"phoneExt":40,"email":88},"Ion Jovin","804-675-5419","ion.jovin@va.gov",{"type":90,"investigatorFullName":40,"investigatorTitle":40,"investigatorAffiliation":40,"oldNameTitle":40,"oldOrganization":40},"SPONSOR","100437910","phase-2-remote-ischemic-preconditioning-for-renal-and-cardiac-protection-in-congestive-heart-failure-rich-trial-100437910",false,"NCT04982419","Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial","RICH","Inclusion Criteria:\n\n* Age 18 years\n* Diagnosis of heart failure with reduced LVEF \\\u003C50%\n* Pre-procedure intravenous normal saline fluid restriction status\n* Society for Cardiovascular Angiography and Interventions (SCAI) AKI risk score (\\>1%)\n* Referral for coronary angiogram and\u002For PCI\n* Suspected stable coronary artery disease or acute coronary syndrome\n\nExclusion Criteria:\n\n* Inability to give informed consent\n* Unstable BP (SBP \\> 200 or \\\u003C80 mmHg) at the time of enrolment\n* Upper limb peripheral arterial disease\n* Unavailability of at least one arm for RIPC\u002FSham-RIPC application\n* Kidney transplant\n* Renal disease requiring dialysis\n* Prior exposure to contrast media within 72hrs preceding coronary angiography\n* Pregnancy\n* Prisoner","ALL","18 Years",{"count":101,"type":102},240,"ESTIMATED","INTERVENTIONAL",[105,106],"PHASE2","PHASE3","This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure undergoing cardiac catheterization and\u002For percutaneous coronary intervention.",[109,110,111,112,113],"Acute Kidney Injury","Heart Failure","Contrast Induced Nephropathy","Coronary Angiography","Percutaneous Coronary Intervention",[115,116,117,118,119,120,121,122,123,124,125],"Contrast-induced acute kidney injury","Congestive heart failure","Contrast induced nephropathy","Coronary angiography","Percutaneous coronary intervention","Coronary artery disease","Remote ischemic conditioning","acute coronary syndrome","Acute kidney injury","Major adverse kidney events","Ischemic preconditioning","2025-12-09",{"date":128,"type":129},"2025-12-15","ACTUAL",{"date":131,"type":129},"2021-11-01",{"date":133,"type":102},"2029-03-31",{"name":5,"class":6},3]