[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484137":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":45,"responsibleParty":70,"collaborators":72,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":26,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":26,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Real M1 High Frequency rTMS","EXPERIMENTAL","Participants will be randomly assigned to receive high-frequency repetitive transcranial magnetic stimulation (rTMS) to the top of their head for approximately 40 minutes.",[13],"Device: High frequency repetitive transcranial magnetic stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham rTMS","SHAM_COMPARATOR","Participants will be randomly assigned to receive sham\u002Fplacebo repetitive transcranial magnetic stimulation (rTMS) to the their head for approximately 40 minutes. This is a control condition.",[19],"Device: Sham repetitive transcranial magnetic stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","High frequency repetitive transcranial magnetic stimulation","MagVenture MagPro X100 with MagOption",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Sham repetitive transcranial magnetic stimulation",[15],[31],{"name":32,"affiliation":33,"role":34},"John H Kindred","Atlanta VA Medical and Rehab Center, Decatur, GA","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","(970) 426-9350","John.Kindred1@va.gov",{"name":41,"role":37,"phone":42,"phoneExt":43,"email":44},"Christina Young","(404) 432-6111","207670","christina.young3@va.gov",[46],{"facility":33,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Decatur","Georgia","30033-4004","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-84.29631,33.77483,{"lat":57,"lon":56},[60,65,69],{"name":61,"role":37,"phone":62,"phoneExt":63,"email":64},"Medina O Bello","404-321-6111","206967","medina.bello@va.gov",{"name":66,"role":37,"phone":42,"phoneExt":67,"email":68},"Kevin Mammino","205396","kevin.mammino@va.gov",{"name":32,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":71,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[73],{"name":74,"class":75},"Joseph Maxwell Cleland VA Medical Center","UNKNOWN","100484137","phase-2-repetitive-transcranial-magnetic-stimulation-a-form-of-non-invasive-brain-stimulation-as-a-possible-treatment-for-post-stroke-fatigue-100484137",false,"NCT05584124","Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue.","Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study","Inclusion Criteria:\n\n* 34 - 80 years of age\n* more than 6 months post-stroke\n* Clinically present fatigue\n\nExclusion Criteria:\n\n* Contraindications to MRI\u002FTMS\u002FrTMS (e.g. implanted metal within the head, history of seizures)\n* Inability to follow simple three-step instructions\n* Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate\u002Fsevere TBI)\n* Pregnancy\n* strokes within stimulation sites\n* Pregnancy\n* Severe hypertension (resting SBP \\> 200, DBP \\> 120)","ALL","34 Years","80 Years",{"count":87,"type":88},60,"ESTIMATED","INTERVENTIONAL",[91],"PHASE2","This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.",[94,95,96],"Stroke","Stroke, Chronic","Fatigue",[98,99,100,101,102],"non-invasive brain stimulation","post-stroke fatigue","perception of fatigue","repetitive transcranial magnetic stimulation","rTMS","2026-04-15",{"date":105,"type":106},"2026-04-21","ACTUAL",{"date":108,"type":106},"2023-04-10",{"date":110,"type":88},"2027-10-29",{"name":5,"class":6},1]